The opportunities and challenges of developing imaging biomarkers to study lung function and disease
DP Schuster - American journal of respiratory and critical care …, 2007 - atsjournals.org
… lung volume, whether a reliable association can be demonstrated between the imaging
biomarker … be daunting if not impossible for costly biomarkers such as imaging. Therefore, to take …
biomarker … be daunting if not impossible for costly biomarkers such as imaging. Therefore, to take …
Standardized airway wall thickness Pi10 from routine CT scans of COPD patients as imaging biomarker for disease severity, lung function decline, and mortality
K Kahnert, RA Jörres, HU Kauczor… - Therapeutic …, 2023 - journals.sagepub.com
… Previous studies addressing the association between Pi10 and lung function decline were
… In the present study, we also evaluated the lung function decline in association with Pi10 …
… In the present study, we also evaluated the lung function decline in association with Pi10 …
Early imaging biomarkers of lung cancer, COPD and coronary artery disease in the general population: rationale and design of the ImaLife (Imaging in Lifelines) Study
C Xia, M Rook, GJ Pelgrim, G Sidorenkov… - European journal of …, 2020 - Springer
… The cohort invited for lung function testing was unselected (primarily based on scheduling
of lung function test slots). However, there was a number of exclusion criteria for lung function …
of lung function test slots). However, there was a number of exclusion criteria for lung function …
MRI and CT lung biomarkers: Towards an in vivo understanding of lung biomechanics
… The primary clinical biomarker of lung function is the spirometry measurement of forced …
and discuss imaging methods required to generate imaging biomarkers of lung biomechanics, …
and discuss imaging methods required to generate imaging biomarkers of lung biomechanics, …
Radiomics and its emerging role in lung cancer research, imaging biomarkers and clinical management: State of the art
… With the development of functional imaging modalities we now have the ability to study the
microenvironment of lung cancer and its genomic instability. Radiomics is defined as the use …
microenvironment of lung cancer and its genomic instability. Radiomics is defined as the use …
Predicting Postoperative Lung Function in Patients with Lung Cancer Using Imaging Biomarkers
OB Kwon, HU Lee, HE Park, JY Choi, JW Kim, SH Lee… - Diseases, 2024 - mdpi.com
… imaging biomarkers. This study aimed to predict postoperative lung function with imaging
biomarkers… A retrospective analysis of 79 patients with lung cancer who had undergone lung …
biomarkers… A retrospective analysis of 79 patients with lung cancer who had undergone lung …
Comparison of the quantitative CT imaging biomarkers of idiopathic pulmonary fibrosis at baseline and early change with an interval of 7 months
HJ Kim, MS Brown, D Chong, DW Gjertson, P Lu… - Academic radiology, 2015 - Elsevier
… This indicates that high kurtosis is associated with mild disease based on lung function. …
(indicating that patients with relatively good lung function are associated with small extent of …
(indicating that patients with relatively good lung function are associated with small extent of …
Using imaging as a biomarker for asthma
… been used to assess regional lung function. Hyperpolarized 3 He … in lung ventilation after
bronchodilator therapy. Further studies are needed to evaluate the optimal imaging biomarker …
bronchodilator therapy. Further studies are needed to evaluate the optimal imaging biomarker …
[HTML][HTML] Mechanism and non-mechanism based imaging biomarkers for assessing biological response to treatment in non-small cell lung cancer
… than is available on anatomical imaging alone. Use of these biomarkers, or other rational …
emission tomography and magnetic resonance imaging biomarker indices is examined and …
emission tomography and magnetic resonance imaging biomarker indices is examined and …
Noninvasive imaging biomarker identifies small airway damage in severe chronic obstructive pulmonary disease
DM Vasilescu, FJ Martinez, N Marchetti… - American journal of …, 2019 - atsjournals.org
… termed “functional small airways disease” (fSAD) (11). Longitudinal imaging studies suggest
… lung function decline even among at-risk individuals initially without airflow obstruction (12). …
… lung function decline even among at-risk individuals initially without airflow obstruction (12). …
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