The opportunities and challenges of developing imaging biomarkers to study lung function and disease
DP Schuster - American journal of respiratory and critical care …, 2007 - atsjournals.org
… lung volume, whether a reliable association can be demonstrated between the imaging
biomarker … impact on drug development or disease management. Establishing such performance …
biomarker … impact on drug development or disease management. Establishing such performance …
[HTML][HTML] Early imaging biomarkers of lung cancer, COPD and coronary artery disease in the general population: rationale and design of the ImaLife (Imaging in …
C Xia, M Rook, GJ Pelgrim, G Sidorenkov… - European journal of …, 2020 - Springer
… The cohort invited for lung function testing was unselected (primarily based on scheduling
of lung function test slots). However, there was a number of exclusion criteria for lung function …
of lung function test slots). However, there was a number of exclusion criteria for lung function …
Noninvasive imaging biomarker identifies small airway damage in severe chronic obstructive pulmonary disease
DM Vasilescu, FJ Martinez, N Marchetti… - American journal of …, 2019 - atsjournals.org
… termed “functional small airways disease” (fSAD) (11). Longitudinal imaging studies suggest
… lung function decline even among at-risk individuals initially without airflow obstruction (12). …
… lung function decline even among at-risk individuals initially without airflow obstruction (12). …
[HTML][HTML] Imaging biomarkers of lung ventilation in interstitial lung disease from 129Xe and oxygen enhanced 1H MRI
… imaging biomarkers from hyperpolarised 129 Xe ventilation MRI and dynamic oxygen-enhanced
MRI (OE-MRI) with standard pulmonary function tests (PFT) in interstitial lung disease (…
MRI (OE-MRI) with standard pulmonary function tests (PFT) in interstitial lung disease (…
Comparison of the quantitative CT imaging biomarkers of idiopathic pulmonary fibrosis at baseline and early change with an interval of 7 months
HJ Kim, MS Brown, D Chong, DW Gjertson, P Lu… - Academic radiology, 2015 - Elsevier
… This indicates that high kurtosis is associated with mild disease based on lung function.
Histogram mean, variance, median, and entropy as well as QLF and QILD scores were inversely …
Histogram mean, variance, median, and entropy as well as QLF and QILD scores were inversely …
MRI and CT lung biomarkers: Towards an in vivo understanding of lung biomechanics
… and distribution of disease in a way that directly reflects lung function and pathophysiology.
… and discuss imaging methods required to generate imaging biomarkers of lung biomechanics…
… and discuss imaging methods required to generate imaging biomarkers of lung biomechanics…
[HTML][HTML] Novel lung imaging biomarkers and skin gene expression subsetting in dasatinib treatment of systemic sclerosis-associated interstitial lung disease
V Martyanov, GHJ Kim, W Hayes, S Du, BJ Ganguly… - PLoS …, 2017 - journals.plos.org
… Patients in the inflammatory gene expression subset showed increase in skin fibrosis,
decreasing pulmonary function and worsening lung fibrosis during the study. These findings …
decreasing pulmonary function and worsening lung fibrosis during the study. These findings …
COPD biomarkers and phenotypes: opportunities for better outcomes with precision imaging
GR Washko, G Parraga - European Respiratory Journal, 2018 - Eur Respiratory Soc
… It slows the decline in lung function and improves survival [1, 2]. Additional … of imaging
biomarkers of lung injury in those at risk for future disease, and 2) utilisation of novel imaging …
biomarkers of lung injury in those at risk for future disease, and 2) utilisation of novel imaging …
Using imaging as a biomarker for asthma
… for measuring pulmonary function biomarkers, which include lung ventilation… imaging
biomarkers are needed to assess whether these treatments are modifying the course of this disease…
biomarkers are needed to assess whether these treatments are modifying the course of this disease…
Imaging Biomarkers of Pulmonary Structure and Function
D Capaldi - 2018 - search.proquest.com
… of pulmonary function test and subject data. The tasks that were included following data
acquisition were: image … Study visits and acquisition of pulmonary function data was performed …
acquisition were: image … Study visits and acquisition of pulmonary function data was performed …
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