Design, synthesis, biological evaluation, molecular docking, DFT calculations and in silico ADME analysis of (benz) imidazole-hydrazone derivatives as promising …
… In this paper, ten hydrazone derivatives bearing an imidazole or benzimidazole nucleus
have been designed, synthesized and evaluated for their antioxidant, antifungal, and anti-…
have been designed, synthesized and evaluated for their antioxidant, antifungal, and anti-…
Synthesis, Biological Activity Evaluation and Molecular Docking of imidazole derivatives possessing hydrazone moiety
H Kekeçmuhammed, M Tapera… - Chemistry & …, 2023 - Wiley Online Library
… are called ADME/T analysis. With this analysis, both chemical and biological properties of
molecules are examined. All calculated parameters are given in Table 4. With this analysis, it …
molecules are examined. All calculated parameters are given in Table 4. With this analysis, it …
Molecular hybrids integrated with imidazole and hydrazone structural motifs: Design, synthesis, biological evaluation, and molecular docking studies
… Finally, the Qik-prop module of the Schrödinger software was used while performing ADME/T
analysis (absorption, distribution, metabolism, excretion, and toxicity) in order to examine …
analysis (absorption, distribution, metabolism, excretion, and toxicity) in order to examine …
… mechanical, virtual screening, molecular docking, molecular dynamics, ADME and antimicrobial activity studies of some new indole-hydrazone derivatives as potent …
… In this study, a new series of indole-5-carbaldehyde hydrazone … The theoretical ADME
profiles of all compounds were … both MEP analysis and geometric optimization analysis for 5i12 …
profiles of all compounds were … both MEP analysis and geometric optimization analysis for 5i12 …
Investigation of Newly Synthesized Fluorinated Isatin-Hydrazones by In Vitro Antiproliferative Activity, Molecular Docking, ADME Analysis, and e-Pharmacophore …
… modeling, spectroscopic analysis, molecular docking, and ADME studies. Fifteen …
further analyzed by using the ADME parameters. This study suggests that fluorinated isatin-hydrazone …
further analyzed by using the ADME parameters. This study suggests that fluorinated isatin-hydrazone …
Synthesis, characterization, PASS analysis and ADMET properties of oxazolone ring containing hydrazone derivatives
P Vijaya, G Sundaraselvan - Materials Today: Proceedings, 2022 - Elsevier
… were examined for ADME and only few … hydrazones and evaluated in-vitro antibacterial
activity, most of the compounds possess better activity [7]. Hydrazones bearing imidazole …
activity, most of the compounds possess better activity [7]. Hydrazones bearing imidazole …
Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular docking studies of new imidazolyl hydrazone derivatives
… their drug-likeness qualities and ADME/T analysis was carried out to examine the drug …
hydrazone and imidazole were combined in one molecule and a series of imidazolyl hydrazone …
hydrazone and imidazole were combined in one molecule and a series of imidazolyl hydrazone …
Design, synthesis and molecular docking and ADME studies of novel hydrazone derivatives for AChE inhibitory, BBB permeability and antioxidant effects
… In this work, 10 new hydrazones (3a–3j) were designed and … It is seen that the carbonyl
group of hydrazones is also very … of Tyr337 and the imidazole ring of His447 for compound 3j. …
group of hydrazones is also very … of Tyr337 and the imidazole ring of His447 for compound 3j. …
THEORETICAL ELECTRONIC PROPERTIES, ADMET PREDICTION, and MOLECULAR DOCKING STUDIES of SOME IMIDAZOLE DERIVATIVES
SÇ Yavuz - Journal of Scientific Reports-A - dergipark.org.tr
… , molecular modeling, and ADME predictions have been … It was done molecular docking
analysis of the imidazole … among the NH of the hydrazone and the carbonyl groups of …
analysis of the imidazole … among the NH of the hydrazone and the carbonyl groups of …
α-amylase Inhibition and In Silico Studies of Novel Naphtho[2,3-d]imidazole-4,9-Dione Linked N-acyl Hydrazones
… predicted ADME analysis of naphtho[2,3-d]imidazole-4,9-dione attached N-acyl hydrazones
are … dosage, a high-quality drug candidate should also have suitable ADME characteristics. …
are … dosage, a high-quality drug candidate should also have suitable ADME characteristics. …
相关搜索
- adme analysis molecular docking
- hydrazide hydrazone adme prediction
- adme properties bioactive sulfonyl hydrazones
- hydrazone moiety imidazole derivatives
- pass analysis hydrazone derivatives
- imidazole hydrazone silico adme analysis
- adme analysis isatin hydrazones
- imidazole hydrazone promising antioxidant
- adme analysis e-pharmacophore modeling
- imidazole hydrazone dft calculations
- imidazole hydrazone biological evaluation
- hydrazide hydrazone derivatives silico adme prediction