… containing 4, 5-disubstituted thiazole as potential antibiofilm, anti-inflammatory and antioxidant agents: Green synthesis, molecular docking and ADME analysis
D Bhosale, A Narale, P Hadimani, M Kokane… - Journal of Molecular …, 2024 - Elsevier
… ADME, we computed and examined several physical characteristics and pharmaceutically
significant attributes for ADME … and elimination (ADME) factors have been analyzed to predict …
significant attributes for ADME … and elimination (ADME) factors have been analyzed to predict …
Synthesis, characterization, thermal properties, antimicrobial evaluation, ADMET study, and molecular docking simulation of new mono Cu (II) and Zn (II) complexes …
… synthesized by two different methods based on hydrazone derivatives 2 and 3. Additionally,
… elemental analysis, FT-IR, mass spectra, and 1 H/ 13 C NMR. Thermogravimetric analysis …
… elemental analysis, FT-IR, mass spectra, and 1 H/ 13 C NMR. Thermogravimetric analysis …
Design, synthesis, and evaluation of a new series of hydrazones as small-molecule akt inhibitors for NSCLC therapy
B Erdönmez, MD Altıntop, G Akalın Çiftçi… - ACS …, 2023 - ACS Publications
… the 1H-imidazole core … analysis of A549 cells treated with IC 50 values of compounds 3a,
3e, 3g, 3i, and cisplatin. At least 10,000 cells were analyzed per sample, and quadrant analysis …
3e, 3g, 3i, and cisplatin. At least 10,000 cells were analyzed per sample, and quadrant analysis …
Design, synthesis, molecular modeling, DFT, ADME and biological evaluation studies of some new 1, 3, 4-oxadiazole linked benzimidazoles as anticancer agents and …
… ADME properties of the potential aromatase inhibitor compound 5a were analyzed by … in
phase studies without a drug molecule due to poor ADME properties. Making some theoretical …
phase studies without a drug molecule due to poor ADME properties. Making some theoretical …
Novel thiomorpholine tethered isatin hydrazones as potential inhibitors of resistant Mycobacterium tuberculosis
… synthesized and characterized novel isatin hydrazones 4(ao) and their … Further, molecular
docking, ADME pharmacokinetic and molecular … In summary, isatin hydrazones 4(ao) and their …
docking, ADME pharmacokinetic and molecular … In summary, isatin hydrazones 4(ao) and their …
An Insight into the Biological Properties of Imidazole‐Based Schiff Bases: A Review
AK Gopalakrishnan, SA Angamaly… - …, 2021 - Wiley Online Library
… Molecular docking, Lipinski's rule of five, and ADME predictions confirmed the vigorous …
-based compounds for conceivable clinical application in the analysis and treatment of …
-based compounds for conceivable clinical application in the analysis and treatment of …
In silico-Based Structural Prediction, Molecular Docking and ADMET Analysis of Novel Imidazo-Quinoline Derivatives as Pf Purine Nucleoside Phosphorylase …
C Mallick, M Mishra, V Asati, V Kashaw… - Current Signal …, 2023 - ingentaconnect.com
… available methods take a longer time for ADME prediction. Due to the poor pharmacokinetics
… by the oxygen atom substituted in the imidazole ring. The three aromatic rings presented in …
… by the oxygen atom substituted in the imidazole ring. The three aromatic rings presented in …
Imidazole as a promising medicinal scaffold: current status and future direction
SS Alghamdi, RS Suliman, K Almutairi… - Drug Design …, 2021 - Taylor & Francis
… ADME analysis was calculated using the SwissADME webserver. To determine whether the
imidazole … , we have selected the most potent imidazole derivatives that demonstrated high …
imidazole … , we have selected the most potent imidazole derivatives that demonstrated high …
Repurposing of benzimidazole scaffolds for HER2 positive breast cancer therapy: An in-silico approach
… ABZ), being another derivative of benzimidazole category, became more popular in the
year … zole, we decided to synthesize benzimidazole hydrazones and evaluate their anti-breast …
year … zole, we decided to synthesize benzimidazole hydrazones and evaluate their anti-breast …
[HTML][HTML] Computational Drug Designing, Synthesis, Characterization and Anti-bacterial Activity Evaluation of Some Mixed Ligand–Metal Complexes of 2 …
… 2-hydroxybenzaldehyde thiosemicarbazone) as primary ligand and imidazole (im), pyridine
(py) … The mixed ligand complexes having imidazole as secondary ligand displayed relatively …
(py) … The mixed ligand complexes having imidazole as secondary ligand displayed relatively …