Counterregulation between thymic stromal lymphopoietin–and IL-23–driven immune axes shapes skin inflammation in mice with epidermal barrier defects

J Li, JM Leyva-Castillo, P Hener, A Eisenmann… - Journal of Allergy and …, 2016 - Elsevier
inflammatory axes and the cytokine network in mouse skin … between these 2 inflammatory
axes. Furthermore, we show that … the TSLP/type 2 axis, whereas skin bacteria are engaged in …

The role of IL‐23 and the IL‐23/TH17 immune axis in the pathogenesis and treatment of psoriasis

G Girolomoni, R Strohal, L Puig… - Journal of the …, 2017 - Wiley Online Library
… There is robust evidence that the IL-23/T H 17 immune axis is a key driver of psoriatic
inflammation, which has led to the development of biologics that specifically target key elements of …

Stress-induced interaction of skin immune cells, hormones, and neurotransmitters

N Pondeljak, L Lugović-Mihić - Clinical therapeutics, 2020 - Elsevier
… in skin inflammation. Thus, the local skin CRH-POMC-ACTH-corticosteroids axis plays a … of
cytokines and chemokines that regulate skin inflammatory and immune responses. Therefore, …

The brain–skin axis in psoriasis—psychological, psychiatric, hormonal, and dermatological aspects

L Marek-Jozefowicz, R Czajkowski… - International journal of …, 2022 - mdpi.com
… of skin immune cells, hormones and neurotransmitters [18,19]. Skin immune cells actively
regulate tissue inflammation with their proinflammatory and anti-inflammatory effects. Stress-…

Skin immune landscape: inside and outside the organism

F Abdallah, L Mijouin, C Pichon - Mediators of inflammation, 2017 - Wiley Online Library
… of inflammatory-mediated diseases. Taken together, the total skin environment favors the
interaction between the immune cells … in skin resulting in T H 2 inflammatory immune response. …

Classification of human chronic inflammatory skin disease based on single-cell immune profiling

Y Liu, H Wang, M Taylor, C Cook… - Science …, 2022 - science.org
… Number of DEGs (adjusted P value < 0.001, absolute log 2 FC > 0.425; on y axis) for
each immune cell population (x axis) for seven AD versus seven HC sample comparisons (left), …

[PDF][PDF] Mast cells as regulators of skin inflammation and immunity

IT Harvima, G Nilsson - Acta dermato-venereologica, 2011 - researchgate.net
… These molecules can modulate the immune system in the skin, eg in psoriasis, atopic … on
the role of mast cells in skin inflammation and immunity. However, the anaphylactic aspects, …

Steroidogenesis in the skin: implications for local immune functions

A Slominski, B Zbytek, G Nikolakis, PR Manna… - The Journal of steroid …, 2013 - Elsevier
inflammatory disorders, autoimmune processes or other skin disorders. In conclusion, the skin
… functions and the development of local or systemic inflammatory or autoimmune diseases. …

Immune regulation of skin wound healing: mechanisms and novel therapeutic targets

J Larouche, S Sheoran, K Maruyama… - Advances in wound …, 2018 - liebertpub.com
inflammation is a major culprit in the dysregulation of normal wound healing, and further
limiting inflammation … to efficiently control inflammation and specific immune cells. This is further …

IL-1 family antagonists in mouse and human skin inflammation

P Martin, JD Goldstein, L Mermoud… - Frontiers in …, 2021 - frontiersin.org
immune cells of the skin (Table 1) and its expression is enhanced in the context of skin
inflammation. … psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis. Journal …