… for the control of immune cell fate, for … genome organization to the control of immune cell
differentiation and function, and discuss how alterations in genome folding may lead to immune …

… appropriate immune responses. … , a genome organized in three dimensions. Below, we
describe the current understanding of 3D genome organization during three unique immune cell …

… and coding regions of the genome, a process instructed by … and accessibility of the underlying
genome. According to classic … studies in immune system and hematopoietic cells strongly …

… in immune response. We observed that enhancers enriched for links to immune response
genes were more cell… are functionally distinct and specifically organized in the human genome. …

… Importantly, impaired transcriptional control in lymphocytes can lead to aberrant immune
cell … in immune cells, with focus on the interplay between 3D genome organization and …

… to dissecting immune regulation in a systematic, genome-wide … systems immunology of
haematopoietic immune cells 12,13 . … cells to communicate with haematopoietic immune cells, by …

… and applications of the 3D genome. We focus on how the 3D organization of genomes has
an impact on the feature of immune cells of innate and adaptive immunity. Furthermore, we …

… from studies in hematopoietic and immune cells regarding the 3D organization of the β-… the
T(H)2 cytokine locus in a dynamic and cell-type-specific fashion (87). Additional studies have …

… genomic profiling of transcriptional and epigenetic cell states, we discuss how they are applied
to investigate immune cells … diverse cell types of the hematopoietic system are organized …

… immunity. How and when was the genomic organization of the MHC, as we see now,
established… Recently, we and others found that the human and mouse genomes contain the …