[HTML][HTML] Immune checkpoint inhibitors in 10 years: contribution of basic research and clinical application in cancer immunotherapy

JB Lee, HR Kim, SJ Ha - Immune Network, 2022 - ncbi.nlm.nih.gov
… Targeting immune evasion via immune checkpoint pathways has changed the treatment …
, eight immune checkpoint inhibitors (ICIs) centered on PD-1 pathway blockade are approved …

Immune checkpoint inhibitors in the treatment of melanoma: from basic science to clinical application

MP Rausch, KT Hastings - Exon Publications, 2017 - exonpublications.com
… benefit from immune checkpoint blockade. Basic science approaches and clinical experience
… to broaden the clinical impact of immune checkpoint blockade by overcoming resistance to …

Checkpoint inhibitors and their application in breast cancer

D Bedognetti, C Maccalli, SBJ Al Bader, FM Marincola… - Breast Care, 2016 - karger.com
immune checkpoints are currently under clinical development. In this review, we summarize
the evidence supporting the implementation of checkpoint inhibition … with checkpoint inhibitor

Research progress and clinical application of predictive biomarker for immune checkpoint inhibitors

K Ma, Q Jin, M Wang, X Li, Y Zhang - Expert Review of Molecular …, 2019 - Taylor & Francis
… Recent studies suggest that a combination of immune checkpoint inhibitors and IFNa-2b
can enhance clinical efficacy in metastatic melanoma [105,106]. Interferon-gamma (IFNγ), a …

Immune checkpoint inhibition: from molecules to clinical application

LS Taams, TD Gruijl - Clinical & Experimental Immunology, 2020 - academic.oup.com
immune checkpoint inhibition and its beneficial role in cancer immunotherapy, the broad role
of checkpoint molecules in immunityclinical applications in the field of immune checkpoint

Immune checkpoint inhibitors for brain metastases in non-small-cell lung cancer: from rationale to clinical application

G Xiao, Z Liu, X Gao, H Wang, H Peng, J Li… - …, 2021 - Taylor & Francis
… biomarkers for immune checkpoint inhibitors in NSCLC patients with BM. In addition, clinical
data … Here, we review the theoretical basis and clinical data for the application of ICIs in the …

Clinical challenges of immune checkpoint inhibitors

M de Miguel, E Calvo - Cancer cell, 2020 - cell.com
… stories have been achieved with immune checkpoint inhibitors (ICIs), but … clinical arena.
Oncolytic viruses such as talimogene laherparepvec or the autologous cellular immunological

The role of PD-1/PD-L1 and application of immune-checkpoint inhibitors in human cancers

Q Tang, Y Chen, X Li, S Long, Y Shi, Y Yu… - Frontiers in …, 2022 - frontiersin.org
… L1 Immune-checkpoint inhibitors and its future prospects. Although PD-1/PD-L1 immune
checkpoint inhibitors … for the application of PD-1/PD-L1 Immune-checkpoint inhibitors in treating …

Clinical development of immune checkpoint inhibitors

A Ito, S Kondo, K Tada, S Kitano - BioMed research …, 2015 - Wiley Online Library
… has been made in the clinical application of cancer immunotherapies. Most notable is the
emergence of immune checkpoint inhibitors. Large-scale clinical trials have shown their …

Current clinical applications and future perspectives of immune checkpoint inhibitors in non‐Hodgkin lymphoma

J Apostolidis, A Sayyed, M Darweesh… - Journal of …, 2020 - Wiley Online Library
checkpoints in these … to the use of such inhibitors when T cells themselves are the target
cells, and consider future approaches to refine clinical trials with immune checkpoint inhibitors in …