Fatal toxic effects associated with immune checkpoint inhibitors: a systematic review and meta-analysis

DY Wang, JE Salem, JV Cohen, S Chandra… - JAMA …, 2018 - jamanetwork.com
Importance Immune checkpoint inhibitors (ICIs) are now a mainstay of cancer treatment.
Although rare, fulminant and fatal toxic effects may complicate these otherwise transformative …

Comparative safety of immune checkpoint inhibitors in cancer: systematic review and network meta-analysis

C Xu, YP Chen, XJ Du, JQ Liu, CL Huang, L Chen… - Bmj, 2018 - bmj.com
… Although both original and updated studies derived from one trial were included in this
network metaanalysis, we extracted treatment-related adverse events data from the study with the …

Association between immune-related side effects and efficacy and benefit of immune checkpoint inhibitors–a systematic review and meta-analysis

S Hussaini, R Chehade, RG Boldt, J Raphael… - Cancer Treatment …, 2021 - Elsevier
immune checkpoint inhibitors (ICIs) has become standard therapy in many tumor sites. The
aim of this study … to determine whether the incidence of immune-related adverse events (irAEs…

Not all immune-checkpoint inhibitors are created equal: meta-analysis and systematic review of immune-related adverse events in cancer trials

B El Osta, F Hu, R Sadek, R Chintalapally… - Critical reviews in …, 2017 - Elsevier
immune checkpoints is a novel approach in cancer therapy. This strategy may trigger
immune … in patients receiving immune checkpoint inhibitors (ICI) targeting only immune cells …

Cardiovascular immunotoxicities associated with immune checkpoint inhibitors: a safety meta-analysis

C Dolladille, J Akroun, PM Morice… - European Heart …, 2021 - academic.oup.com
Immune checkpoint inhibitor, Cancer, Safety meta-analysis, Randomized clinical trials See
page 4978 for the editorial comment for this article ‘Immune checkpoint inhibitors … the immune

Efficacy and predictive factors of immune checkpoint inhibitors in metastatic breast cancer: a systematic review and meta-analysis

Y Zou, X Zou, S Zheng, H Tang… - … in medical oncology, 2020 - journals.sagepub.com
… In this study, we performed a systematic review and meta-analysis of the reported clinical
trials to evaluate the response and safety of immune checkpoint therapy in patients with …

[HTML][HTML] Association of steroids use with survival in patients treated with immune checkpoint inhibitors: a systematic review and meta-analysis

F Petrelli, D Signorelli, M Ghidini, A Ghidini… - Cancers, 2020 - mdpi.com
Immune checkpoint inhibitors (ICIs) can elicit toxicities by inhibiting negative regulators of
adaptive immunity. … We performed a systematic review and meta-analysis of published studies …

Meta-analysis of quality of life in cancer patients treated with immune checkpoint inhibitors

BD Gonzalez, SL Eisel, KE Bowles… - JNCI: Journal of the …, 2022 - academic.oup.com
Meta-analysis of within-group change in global quality of life in patients receiving immune
checkpoint inhibitor therapy. Positive values indicate improvement. Random effect models …

[HTML][HTML] Tumor mutational burden and efficacy of immune checkpoint inhibitors: a systematic review and meta-analysis

JY Kim, A Kronbichler, M Eisenhut, SH Hong… - Cancers, 2019 - mdpi.com
Tumor mutational burden (TMB) is a genomic biomarker that predicts favorable responses to
immune checkpoint inhibitors (ICIs). Here, we set out to assess the predictive value of TMB …

Immune-related adverse events and survival in solid tumors treated with immune checkpoint inhibitors: a systematic review and meta-analysis

F Petrelli, G Grizzi, M Ghidini, A Ghidini… - Journal of …, 2020 - journals.lww.com
… We performed a systematic review and meta-analysis of the published literature to assess …
introduction of immune checkpoint inhibitors (ICIs). The blockage of immunologic checkpoints […