… Stat3 activity in melanoma negatively regulates infiltration of diverse immune effector cells
and that targeting Stat3 in tumor cells … recruiting immune cells and eliciting innate immune cell-…

… STAT3 activity propagates from tumour cells to immune cells in the tumour microenvironment,
thereby mediating immune … cells and regulatory T cells, and by activating effector cells …

… any efforts to block STAT3 activity in cancer cells are likely to … on host immune responses
mediated through NK cells. It is … and adaptive immunity, effector cells and APCs, cell migration …

… of STAT3 AD-HIES (eg, impaired skin and lung immunity) was … cells require the combined
activity of cytokines from STAT3-dependent, IL-17-producing CD4 + T lymphocytes (Th17 cells) …

… , increased Stat3 activity in APCs resulted in impaired T cell … of T cell tolerance occurs in mice
with an intact Stat3 signaling in … PEM trigger effector function of clonotypic CD4 + T cells, as …

… We propose that tumor Stat-3 activity can mediate immune evasion by blocking both the …
of the antigen processing and presentation machinery critical for effector T cells 32,33,34 , our …

… the activities of IL-15 DCs in the initiation and maintenance of immune effector responses. …
MAPK) and STAT3 activities that underlie the strong immune effector functions of IL-15 DCs. …

… T-cell effector functions such as CD8 + T-cell, γδ T-cell generations … activities of TAMs correlate
with over-activated STAT3 … of TAMs STAT3 activity can enhance rat immune response to …

… Increased Stat3 activity in tumor-associated immune cells promotes immunosuppressive …
for the terminal differentiation of Th17 cell into effector cells in a Stat3-dependent fashion (…

… obesity negatively impacts antitumor immune responses remains largely … STAT3 in CD8 +
T effector cells is critical for obesity-associated breast tumor progression. Ablating T cell Stat3 …