… This study did not assess cytolytic activity, so the role of STAT4 in CTL effector function has
… was shown to be bound not only by STAT3 (in the human NK cell line YT) but also by IL-2-…

… Innate effector cells, including innate effector cells of myeloid … of various types of immune
responses. Bone marrow … STAT3 has been demonstrated to enhance MITF activity in …

… activity, whereas increasing evidence suggests that in humans, activated T effector cells (…
Thus, the anergic state of suppressed Teff cells is not due to induced expression of FOXP3. …

… high activity of NF-κB or STAT3 … effector cells in inflammation. Similar to TAMs, TANs are
classified as N1 neutrophils with an anti-tumor activity and N2 neutrophils with pro-tumor activity […

… activity when compared with an empty pGL4 vector (pGL3 EV). (D) Both Stat3 and Stat5
increased luciferase activity of … effector cytokines, including IL-17A, promoting effector T-cell …

… Constitutive Stat3 DNA-binding activity is inhibited by AG490 … of Stat3 activity occurring
within 16–24 hr in U266 cells (… constitutive Stat3 activation observed in U266 myeloma cells …

… of immune cell differentiation and function. We review here the current understanding of
mTOR and STAT interactions in T cells and innate immune cells, and … mTORC2 activity is often …

… An important feature of the adaptive immune response is its … effector T cells have been
shown to limit excessive immune … not examine whether STAT3 also regulated activities of FoxO …

… and suggest that in addition to promoting Th17 disease-inducing activities, STAT3
activation in CD8 + T cells may further undermine the recovery from EAU by inhibiting the …

… Stat3 plays in regulating DC activity, the Stat3 gene was targeted for deletion with a CD11c-cre
transgene. Stat3 … activity and direct effector T cell differentiation [eg, IFN-γ–producing Th1 …