… effector YopM inhibits effector triggered immunity and increases production of the anti-inflammatory
cytokine Interleukin-10 (IL-10) to suppress the host immune … and RSK activity. We …

… effector cells to A375 target cells was 3.5:1 when using cells … the effects of STAT3 inhibition
on human Treg activity, but this … functional activity, we had to approach our analysis of STAT3 …

… In Stat3 deficient pro-B cells, the activities of Complex I and Complex II are reduced, but …
progression and immunological effector function. Targeting nuclear functions of Stat3 has been …

… STAT3 activation in neutrophil, NK cells and effector T cells also has immunosuppressive …
It is known that STAT3 regulates stability and activity of HIF-1α, inducing expression of …

… the number, functions, and activity of the immune effector cells, including the natural killer
(… , particularly the equilibrium state between cytotoxic/suppressive cells and their localization …

… In a mouse model, migration of these cells into the colon … cells to promote activation of the
transcription factor STAT3 and … The DOT1L complex induced the core stem cell genes NANOG, …

… effector cells for antimicrobial killing typically stems from the classical pathway of activation
by T cell- or NK cell-… genes induced by STAT3 transcriptional activity because the inhibitory …

… characterized the biologic activity of the FLLL32 curcumin analog on human melanoma and
immune effector cells. Our data indicate that FLLL32 can inhibit STAT3 phosphorylation and …

… other activities, act as chemoattractants to recruit additional monocytes and effector cells. …
signal transducer and activator of transcription 3 (STAT3), leading to an enhanced NF-κB …

… 4 – Citation 6 as well as infiltrating immune effector cells (reviewed in refs. Citation7–Citation…
) STAT3 compared with DC from naïve mice.Citation 9 Tumour-induced STAT3 activity …