… 4 – Citation 6 as well as infiltrating immune effector cells (reviewed in refs. Citation7–Citation…
) STAT3 compared with DC from naïve mice.Citation 9 Tumour-induced STAT3 activity …

… gene or neutralizing antibodies targeted against the effector cytokine.16-18 … PIAS3 controls
the extent and duration of STAT3 activity in normal cells and prevents its oncogenic function.…

… that STAT3 positively regulates TGF-β1 promoter activity … of naive, effector, and memory
state of immune cells. Their … that STAT3 and SOCS3 reciprocally regulate Th cell function …

… STAT3 activity supports tumor cell survival by upregulating … NK cells—another important
innate effector cell population—can be triggered and restored by disrupting STAT3 in tumor cells …

… helper T subsets required to deal with different classes of pathogens but provides each of
these distinct effector cells with a mechanism to regulate their own inflammatory activities. …

… Our data suggested that systemic sunitinib treatment reduced tumor dendritic cell Stat3 activity
… -infiltrating Tregs, and activation of CD8 + effector cells (17). Furthermore, recent studies …

… IL-23 promotes protumor immunity through STAT3 activation by … Moreover, infiltration of
effector cells such as CTLs in tumors … activity of effector T cells, including IFN-γ-producing Th1 …

… potent effector cells of innate immunity, the activation of Stat3 in … argue for the notion of
Stat3 as the anti-inflammatory … modifications of Stat3 on its transcriptional activity, and possibly …

… that STAT3 promotes and preserves memory cell potential in virus-specific CD8 + T cells by
… To examine the role of STAT3 in effector and memory CD8 + T cell development during viral …

… used four immune effector molecules as indicators of T cell … suggest that tumor cells
counteract activated T cells by STAT3-… inhibitor of STAT3 with early evidence of clinical activity in …