过去一年中添加的文章,按日期排序

Exploring the crosstalk mechanism and immune relationship between SARS-CoV-2 infection and IgA nephropathy based on comprehensive bioinformatics analysis …

Z Gong, Q Che, M Hu, H Zhang, N Liang, H Li, T Song… - 2024 - researchsquare.com
3 天前 - Background: COVID-19 is a disease caused by SARS CoV-2 infection and has
caused a global pandemic. Currently, it remains a threat to global human health. IgA …

Understanding the mechanisms and treatments of long COVID to address future public health risks

B Li, J Bai, Y Xiong, D Guo, B Fu, G Deng, H Wu - Life Sciences, 2024 - Elsevier
3 天前 - … Considering the potential inflammatory imbalance associated with SARS-CoV-2,
similar aberrant immune responses and inflammatory reactions may persist in a chronic, non-…

[HTML][HTML] Structure of SARS-CoV-2 MTase nsp14 with the inhibitor STM957 reveals inhibition mechanism that is shared with a poxviral MTase VP39

E Zilecka, M Klima, M Stefek, M Dejmek… - Journal of Structural …, 2024 - Elsevier
3 天前 - … This capping is crucial for efficient viral RNA translation, stability, and immune
evasion. Our previous research identified nsp14 inhibitors based on the chemical scaffold of its …

Immunological and homeostatic pathways of alpha-1 antitrypsin: a new therapeutic potential

C Mazzuca, L Vitiello, S Travaglini, F Maurizi… - Frontiers in … - frontiersin.org
3 天前 - … by a chronic immune response. The aim of this review is to provide an up-to-date
understanding of the molecular mechanisms and regulatory pathways responsible for immune-…

[HTML][HTML] SARS-CoV-2 E protein interacts with BRD2 and BRD4 SEED domains and alters transcription in a different way than BET inhibition

N Lara-Ureña, E Gómez-Marín… - Cellular and Molecular …, 2024 - Springer
5 天前 - … BET inhibition has also been indicated to be useful in hampering the exacerbated
immune response associated with SARS-CoV-2 infection and linked to severe tissue damage …

Cannabinoids Targeting SARS-CoV-2 Papain-Like Protease Protein: Molecular Docking Studies & Therapeutic Implications

JTL Holmes - 2024 - search.proquest.com
5 天前 - … A malignant response can be observed after the immune cells retaliate against the
viral SARS-CoV-2, leading to the abnormal secretion of cytokines. After the downregulation …

Canine Coronavirus Infection Alters the Cell Derived-Extracellular Vesicles Biogenesis and Pharmacological-Mediated Cellular Activity

R Pandit - 2024 - search.proquest.com
5 天前 - SARSCoV-2 is an enveloped … type SARS-CoV-2 or previous SARS-CoV2 variants
before Omicron), the receptor binding domain on the S1 subunit of S protein of SARS-CoV-2 …

Uncovering Novel Functions of Viral Accessory Proteins

HT Wong - 2024 - search.proquest.com
5 天前 - … Although suppression of innate immune signaling is believed to be its primary
function, SARS CoV-1 ORF6 also packages into nascent viral particles and induces membrane …

Harnessing Genomic Surveillance to Characterize the Molecular Epidemiology and Uncover Antiviral Resistance Mechanisms of SARS-CoV-2

TL Hu - 2024 - search.proquest.com
5 天前 - … , we examined the impact of remdesivir on SARSCoV-2 diversity and evolution
in vivo. … The epithelial damage in the lungs triggers the host immune response. SARS-CoV-2 …

Manipulation of the Type I Interferon Response Prior to mRNA Vaccination Enhances Immunity Against SARS-CoV-2 in a Murine Model of Infection

AM Dickson - 2024 - search.proquest.com
5 天前 - … Utilizing innate immune mechanisms for immune enhancement ..........................................
25 Innate immunity: the … Viral mechanisms used for replication enhancement via innate …