[HTML][HTML] Host immune response driving SARS-CoV-2 evolution

R Wang, Y Hozumi, YH Zheng, C Yin, GW Wei - Viruses, 2020 - mdpi.com
… analysis of existing SARS-CoV-2 mutations. We reveal that host immune response via …
and Africa react significantly more intensively to SARS-CoV-2 infection than those of Europe …

Exploring the role of immune system and inflammatory cytokines in SARS-CoV-2 induced lung disease: a narrative review

C Tirelli, M De Amici, C Albrici, S Mira, G Nalesso, B Re… - Biology, 2023 - mdpi.com
SARS-CoV-2 infection may induce an over activation of the immune system and the release
… storm”, a recognized pathogenetic mechanism in the genesis of SARS-CoV-2-induced lung …

The journey of SARS-CoV-2 in human hosts: a review of immune responses, immunosuppression, and their consequences

AF Alshammary, AM Al-Sulaiman - Virulence, 2021 - Taylor & Francis
… a disrupted immune response, which is alarming, as immune … collating information about
the mechanisms underlying this … emergence of SARS-CoV-2, conclusive data on SARS-CoV-…

Between immunomodulation and immunotolerance: The role of IFNγ in SARS-CoV-2 disease

N Todorović-Raković, JR Whitfield - Cytokine, 2021 - Elsevier
… implicated in various immune mechanisms such as … SARS-CoV-2. A recent study uncovered
the possibility of differences in the antiviral immune response between IAV and SARS-CoV-…

From SARS to SARS-CoV-2, insights on structure, pathogenicity and immunity aspects of pandemic human coronaviruses

N Kirtipal, S Bharadwaj, SG Kang - Infection, Genetics and Evolution, 2020 - Elsevier
… and genotypic classification, and pathogenesis of SARS-CoV-2 for the production of … known
pandemic virus against SARS-CoV-2. We also consider the host immune response and viral …

Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of …

H Chu, JFW Chan, Y Wang, TTT Yuen… - Clinical Infectious …, 2020 - academic.oup.com
… replication capacity and immune activation profile of SARS-CoV-2 and SARS-CoV infection
in … transmissibility of COVID-19 and the innate immune mechanism behind this phenomenon. …

Potential molecular mechanisms of rare anti-tumor immune response by SARS-CoV-2 in isolated cases of lymphomas

D Barh, S Tiwari, L Gabriel Rodrigues Gomes… - Viruses, 2021 - mdpi.com
… However, the precise molecular mechanism of this rare event is yet to be … -tumor immune
response of SARS-CoV-2 and based on a computational approach show that: (i) SARS-CoV-2 …

SARS-CoV-2 infection: host response, immunity, and therapeutic targets

P Shivshankar, H Karmouty-Quintana, T Mills… - Inflammation, 2022 - Springer
… Currently, the understanding of SARS-CoV-2 immunopathogenesis relies heavily on human
… , including SARS-CoV and MERS [61]. Innate immune sensing of SARS-CoV-2 is mediated …

SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity

W Zhang, BY Chua, KJ Selva, L Kedzierski… - Nature …, 2022 - nature.com
Respiratory tract infection with SARS-CoV-2 results in varying immunopathology underlying
COVID-19. We examine cellular, humoral and cytokine responses covering 382 immune

Immunological mechanisms of vaccine-induced protection against SARS-CoV-2 in humans

K Goyal, H Goel, P Baranwal, A Tewary, A Dixit… - Immuno, 2021 - mdpi.com
… innate immune system [14,15]. Several observations highlight the critical role of … immunity
in SARS-CoV-2 regulation. Human coronaviruses such as SARS, MERS, and SARS-CoV