… biomaterial-immune system interactions. Then, we discuss how the immune response can be
tuned by … -immune response to implanted biomaterials and to promote tissue regeneration. …

… to a foreign object is known as foreign body response (FBR). … in the initiation of immune
responses such as inflammation … increase the immune response of the host to a foreign body. …

… immunity. The consistent diagnosis of the foreign body reaction with macrophages and foreign
body … interfaces and the persistence of the foreign body response prompted our interest in …

… detrimental immune responses. In this article, we provide an overview of immune responses
… host reactions while supporting pro-healing immune responses. We also review existing in-…

… Typical pattern recognition receptors (PRR) for these danger signals are Toll-like receptors
(TLR), which are able to initiate the innate immune response.29 In addition to DAMP, …

… that is responsible for protecting against damaging foreign pathogens, maintaining … adaptive
immunity and how the immune system recognizes and eliminates or reacts to foreign bodies …

The efficacy of implanted biomedical devices is often compromised by host recognition and
subsequent foreign body responses. Here, we demonstrate the role of the geometry of …

… foreign body reaction are generally considered to be early events occurring in the innate
immune response , … in the innate and acquired immune responses must be appreciated within …

… series of distinct immune and repair-like responses that are collectively known as the foreign
body reaction (FBR). These include processes involving innate immune inflammatory cells …

… myeloid-derived suppressor cell subset that prevents excessive immune responses [38]. …
In this study inhibition of VEGF positively impacted the foreign body response, however, for …