Molecular mechanism and function of CD40/CD40L engagement in the immune system
R Elgueta, MJ Benson, VC De Vries… - Immunological …, 2009 - Wiley Online Library
… response (64). In contrast to the TD immune response, abrogation of the CD40/CD40L
pathway has no impact on the thymus-independent (TI) antibody response. When mice are …
pathway has no impact on the thymus-independent (TI) antibody response. When mice are …
[HTML][HTML] CD40/CD40 ligand interactions in immune responses and pulmonary immunity
T Kawabe, M Matsushima, N Hashimoto… - Nagoya journal of …, 2011 - ncbi.nlm.nih.gov
… immunity. The focus of this review is on the role of the CD40L/CD40 costimulatory system in
… Comprehensive reviews on the overall biology of the CD40L/CD40 system can be found in …
… Comprehensive reviews on the overall biology of the CD40L/CD40 system can be found in …
Differential CD40/CD40L expression results in counteracting antitumor immune responses
G Murugaiyan, R Agrawal, GC Mishra… - The Journal of …, 2007 - journals.aai.org
… CD40-CD40L gene doses elicit different levels and functionally counteracting phenotypes of
T cell responses … on the strength of its CD40-CD40L-mediated cognate interaction with CD4 …
T cell responses … on the strength of its CD40-CD40L-mediated cognate interaction with CD4 …
The CD40/CD40L costimulatory pathway in inflammatory bowel disease
S Danese, M Sans, C Fiocchi - Gut, 2004 - gut.bmj.com
… contributor, the CD40/CD40 ligand (L) system, and present evidence that this system plays a
major role in immunity and inflammation… fits in the general scheme of an immune response. …
major role in immunity and inflammation… fits in the general scheme of an immune response. …
Humoral immune responses in CD40 ligand-deficient mice.
BR Renshaw, WC Fanslow 3rd, RJ Armitage… - The Journal of …, 1994 - rupress.org
… responses to opportunistic bacterial infections. To address the role of CD40L in humoral
immunity, we created, through homologous recombination, mice deficient in CD40L expression. …
immunity, we created, through homologous recombination, mice deficient in CD40L expression. …
[PDF][PDF] CD40/CD40L dyad in the inflammatory and immune responses in the central nervous system
… where CD40 cross-linking occurs (5). In immune system, CD40CD40L interaction affects
some key processes, ie, immune cell activation, differentiation, proliferation, and apoptosis. …
some key processes, ie, immune cell activation, differentiation, proliferation, and apoptosis. …
Role for CD40–CD40 ligand interactions in the immune response to solid tumours
AB Alexandroff, AM Jackson, T Paterson, JL Haley… - Molecular …, 2000 - Elsevier
… of immune cells. In the current study we examined the role of CD40-mediated interactions in
immune responses … lines using soluble human CD40L (rhCD40L) or anti-CD40 mAb in vitro. …
immune responses … lines using soluble human CD40L (rhCD40L) or anti-CD40 mAb in vitro. …
Functions of CD40 and its ligand, gp39 (CD40L)
JD Laman, E Claassen… - Critical Reviews™ in …, 2017 - dl.begellhouse.com
… dependent on signals provided through the CD40-CD40L interaction. However, novel …
CD40L and CD40 molecules may extend well beyond their role in the humoral immune response…
CD40L and CD40 molecules may extend well beyond their role in the humoral immune response…
Mechanistic basis of co-stimulatory CD40-CD40L ligation mediated regulation of immune responses in cancer and autoimmune disorders
… of cell-mediated and humoral adaptive immunity (Pype et al., … of the CD40 with a deregulated
amount of CD40 ligand has … of CD40-CD40L mediated regulation of immune response …
amount of CD40 ligand has … of CD40-CD40L mediated regulation of immune response …
The Cd40 ligand: The center of the immune universe?
IS Grewal, RA Flavell - Immunologic research, 1997 - Springer
… have studied immune responses of CD40Ldeficient mice following infection with these
viruses (65). Our results indicated severely compromised humoral immune responses in CD40L-…
viruses (65). Our results indicated severely compromised humoral immune responses in CD40L-…
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