… However, little is known about the molecular mechanisms by which adaptive immunity may
fine-tune the innate immune responses, since the latter is deemed to be the frontline defense. …

… an immune response by releasing different cytokines or chemokines. An additional mechanism
… the intestinal response of immunoglobulin A and the mitigation of intestinal inflammatory …

… of an adaptive immune response and is often referred to as intrinsic asthma [32]. It has been
proposed that the newly discovered innate lymphoid ILC2 cells drive this type of disease in …

… Here, we highlight recent advancements in immunogenetics and provide a forward-looking
view of the innovations that will deliver mechanistic insights from human genetics. …

… This capacity impacts nearly every aspect of the immune system including, among … immune
surveillance [9], and the generation and regulation of innate and adaptive immune responses …

… probe the immune system and the computational tools used to extract relevant biological
information that can be used to gain mechanistic insights and/or to identify immune biomarkers. …

… In summary, dysregulated immune responses against microbial antigens and LDL initiate …
is vital to integrate mechanistic links on how the innate and adaptive immune responses are …

… The answers to these questions may rely on our in-depth understanding of the basic
mechanisms of the cancer immune response, immunotherapeutic efficacy, and resistance. …

… emerging fungal pathogens, yet mechanistic insights into its immune recognition and
control are lacking. Here, we integrate transcriptional and functional immune-cell profiling to …

… of host immune responses … mechanistic association between T-cell immunosenescence
and human immunodeficiency virus (HIV) disease progression, and functional T-cell responses …