Mechanistic insights into eosinophilic esophagitis: therapies targeting pathophysiological mechanisms

S Massironi, G Mulinacci, C Gallo, A Elvevi, S Danese… - Cells, 2023 - mdpi.com
immune response triggered by exposure to allergens, often derived from food [2,6]. This
immune response … allergen sensitization, Th2 immune response, epithelial barrier dysfunction, …

Mechanistic insight into lymphocyte activation through quantitative imaging and theoretical modelling

B Treanor, FD Batista - Current opinion in immunology, 2007 - Elsevier
… of such quantitative data providing mechanistic insight into lymphocyte activation. …
modelling to integrate this complex data to gain mechanistic insight into lymphocyte activation. …

“Complimenting the complement”: mechanistic insights and opportunities for therapeutics in hepatocellular carcinoma

A Malik, U Thanekar, S Amarachintha, R Mourya… - Frontiers in …, 2021 - frontiersin.org
… The complement system, an integral component of the antitumor immune response, acts
as an intrinsic effector mechanism to form a functional bridge between the innate and the …

A review of mechanistic insight and application of pH-sensitive liposomes in drug delivery

SR Paliwal, R Paliwal, SP Vyas - Drug delivery, 2015 - Taylor & Francis
… These vesicles have also been widely explored for antigen delivery and serve as immunological
adjuvant to enhance the immune response to antigens. The present review deals with …

New insights into the immune functions of complement

ES Reis, DC Mastellos, G Hajishengallis… - Nature Reviews …, 2019 - nature.com
mechanism during a T cell immune response 105 . It has been suggested that co-ligation
of MCP and CD35 on activated CD4 + T cells further potentiates the production of IL-10 by …

[HTML][HTML] New developments providing mechanistic insight into the impact of the microbiota on allergic disease

KD McCoy, Y Köller - Clinical immunology, 2015 - Elsevier
… to gain mechanistic insight into how bacteria can shape an allergic immune response from …
recent studies that have started to provide mechanistic understanding into how the microbiota …

B cells in neuroinflammation: new perspectives and mechanistic insights

JJ Ahn, M Abu-Rub, RH Miller - Cells, 2021 - mdpi.com
… properties and discuss evidence supporting the emerging concept that B cells play a critical
role in regulating adaptive and innate immune responses in various neurological disorders. …

[HTML][HTML] New immunosuppressive drugs: mechanistic insights and potential therapeutic advances

AW Thomson, TE Starzl - Immunological reviews, 1993 - ncbi.nlm.nih.gov
… (iii) Mechanistic concepts Generation of a T-cell-mediated immune response leading … with
receipt of a second co-stimulatory signal and the response of T helper 1 (T H1 ) cells to the …

TLR Agonists as Mediators of Trained Immunity: Mechanistic Insight and Immunotherapeutic Potential to Combat Infection

JL Subiza - Trained Immunity-based Vaccines, 2021 - books.google.com
… therapies that boost host immune responses and protect … immune responses relies on the
induction of innate immune … localization as a mechanism to fine-tune the immune response. In …

Mechanistic insights into the role of C-type lectin receptor/CARD9 signaling in human antifungal immunity

RA Drummond, MS Lionakis - Frontiers in cellular and infection …, 2016 - frontiersin.org
… bind fungal carbohydrates and initiate antifungal immune responses. Accordingly, human
CARD9 … advances that have provided significant mechanistic insights into the pathogenesis of …