Transcriptional activation of inflammatory genes: mechanistic insight into selectivity and diversity
AU Ahmed, BRG Williams, GE Hannigan - Biomolecules, 2015 - mdpi.com
… Toll-like receptors (TLR) 4-mediated signaling of innate immune responses. Binding of …
Toll-like receptors (TLR) 4-mediated signaling of innate immune responses. Binding of …
Toll-like receptors (TLR) 4-mediated signaling of innate immune responses. Binding of …
A mechanistic insight into the pathogenic role of interleukin 17A in systemic autoimmune diseases
R Bisoendial, E Lubberts - Mediators of Inflammation, 2022 - Wiley Online Library
… immune response to microbial inflammation and the development of autoimmune disorders.
RNA-binding proteins (RBPs), like AT-rich interactive domain-containing protein 5A (arid5a)…
RNA-binding proteins (RBPs), like AT-rich interactive domain-containing protein 5A (arid5a)…
Combining mathematical models with experimentation to drive novel mechanistic insights into macrophage function
JE Jansen, EA Gaffney, J Wagg, MC Coles - Frontiers in immunology, 2019 - frontiersin.org
… immune responses, tissue homeostasis, and immune … in IBD pathophysiology, the mechanistic
details of this role remain to … Furthermore, mechanistic understanding of the role of drug …
details of this role remain to … Furthermore, mechanistic understanding of the role of drug …
New insights into immune-mediated mechanisms in Parkinson's disease
JSY Tan, YX Chao, O Rötzschke, EK Tan - International Journal of …, 2020 - mdpi.com
… may provide novel mechanistic insights on PD pathogenesis. … By focusing on immune-mediated
pathways, this review aims … axis and innate and adaptive immune responses that may be …
pathways, this review aims … axis and innate and adaptive immune responses that may be …
MicroRNAs: A new paradigm towards mechanistic insight of diseases.
… -cells but the regulating mechanism is still not clear. However, it has been … immunity against
viruses, bacteria and other pathogens. The development and regulation of adaptive immune …
viruses, bacteria and other pathogens. The development and regulation of adaptive immune …
Mechanistic insights into cellular immunity of chondroitin sulfate A and its zwitterionic N-deacetylated derivatives
W Zhang, F Sun, H Niu, Q Wang, J Duan - Carbohydrate polymers, 2015 - Elsevier
… In this study, we determined the signaling pathway involved in immune response of CS and
… Thus, our finding provided a mechanistic insight into the understanding of cellular immunity …
… Thus, our finding provided a mechanistic insight into the understanding of cellular immunity …
Mechanistic insights into the efficacy of cell penetrating peptide-based cancer vaccines
M Grau, PR Walker, M Derouazi - Cellular and Molecular Life Sciences, 2018 - Springer
… Accordingly, we demonstrated that the choice of adjuvant directly impacts on the immune
responses and subsequent anti-tumor effects elicited by CPP-based cancer vaccines. We …
responses and subsequent anti-tumor effects elicited by CPP-based cancer vaccines. We …
Mechanistic insights into the role of B cells in rheumatoid arthritis
… However, the pathway through which B lymphocytes contribute to the immune response
is uncertain. They conclusively found B cells which are antigen definite play essential roles …
is uncertain. They conclusively found B cells which are antigen definite play essential roles …
Mechanistic insights into immune checkpoint inhibitor-related hypophysitis: a form of paraneoplastic syndrome
K Kanie, G Iguchi, H Bando, S Urai, H Shichi… - Cancer Immunology …, 2021 - Springer
… Because of enhanced immune responses, immune-related adverse events (irAEs), including
endocrinopathies such as hypophysitis, have been associated with the use of ICIs. Most …
endocrinopathies such as hypophysitis, have been associated with the use of ICIs. Most …
Tumor metastasis: Mechanistic insights and therapeutic interventions
M Liu, J Yang, B Xu, X Zhang - MedComm, 2021 - Wiley Online Library
… in TME by inhibiting adaptive and innate immune responses. Here, we summarized the …
For example, Tregs impede CD8+T cell-mediated anti-tumor immune responses by inhibiting …
For example, Tregs impede CD8+T cell-mediated anti-tumor immune responses by inhibiting …