The microbiome in systemic autoimmune disease: mechanistic insights from recent studies
C Dehner, R Fine, MA Kriegel - Current opinion in rheumatology, 2019 - journals.lww.com
… protective immunity against pathogens and prevent inflammatory immune responses against
… other isotypes marks pathobionts that elicit systemic immune responses as seen in non-gut …
… other isotypes marks pathobionts that elicit systemic immune responses as seen in non-gut …
Mechanistic insights into immune checkpoint inhibitor-related hypophysitis: a form of paraneoplastic syndrome
K Kanie, G Iguchi, H Bando, S Urai, H Shichi… - Cancer Immunology …, 2021 - Springer
… Because of enhanced immune responses, immune-related adverse events (irAEs), including
endocrinopathies such as hypophysitis, have been associated with the use of ICIs. Most …
endocrinopathies such as hypophysitis, have been associated with the use of ICIs. Most …
Tumor metastasis: Mechanistic insights and therapeutic interventions
M Liu, J Yang, B Xu, X Zhang - MedComm, 2021 - Wiley Online Library
… in TME by inhibiting adaptive and innate immune responses. Here, we summarized the …
For example, Tregs impede CD8+T cell-mediated anti-tumor immune responses by inhibiting …
For example, Tregs impede CD8+T cell-mediated anti-tumor immune responses by inhibiting …
The pursuit of transplantation tolerance: new mechanistic insights
PK Gupta, CM McIntosh, AS Chong… - Cellular & Molecular …, 2019 - nature.com
… phase of the immune response within secondary … immune cell effector functions; thus,
Tbet + , IRF4 + , STAT-3/RORγt + , Bcl6 + Tregs can inhibit Th1, Th2, Th17, and Tfh responses, …
Tbet + , IRF4 + , STAT-3/RORγt + , Bcl6 + Tregs can inhibit Th1, Th2, Th17, and Tfh responses, …
Mechanistic insights into the impact of air pollution on pneumococcal pathogenesis and transmission
… of immune cells to the site of infection. However, an overactivated immune response may …
the impact that air pollution has on the immune responses that play a key role in controlling …
the impact that air pollution has on the immune responses that play a key role in controlling …
Vitiligo: mechanistic insights lead to novel treatments
ML Frisoli, JE Harris - Journal of Allergy and Clinical Immunology, 2017 - Elsevier
… Existing treatments for vitiligo (Table I) include topical steroids and calcineurin inhibitors,
which suppress immune responses in the superficial skin, where the immune infiltrate is located…
which suppress immune responses in the superficial skin, where the immune infiltrate is located…
Evidence-based and mechanistic insights into exclusion diets for IBS
… In addition, the immune response related to food might be atypical and not driven by IgE.
A novel approach has been described 40 in which patients with IBS who did not show an IgE …
A novel approach has been described 40 in which patients with IBS who did not show an IgE …
Mechanistic insights into ADXS11-001 human papillomavirus-associated cancer immunotherapy
… Dendritic cells are an important link between the innate and adaptive immune responses,
with their activation in response to the TLR signaling cascade required for co-stimulation of T …
with their activation in response to the TLR signaling cascade required for co-stimulation of T …
Immune evasion, a potential mechanism of trichothecenes: new insights into negative immune regulations
Q Wu, W Wu, TCC Franca, V Jacevic, X Wang… - International Journal of …, 2018 - mdpi.com
… system to allow pathogens to escape the host immune response [2]. We further suspect that
the immune evasion mechanism may have a relationship with the autophagy process, since …
the immune evasion mechanism may have a relationship with the autophagy process, since …
A review on possible mechanistic insights of Nitazoxanide for repurposing in COVID-19
AS Lokhande, PV Devarajan - European Journal of Pharmacology, 2021 - Elsevier
… Furthermore, nitazoxanide displays the potential to boost host innate immune responses
and thereby tackle the life-threatening cytokine storm. Possibilities of improving lung, as well as …
and thereby tackle the life-threatening cytokine storm. Possibilities of improving lung, as well as …