Obesity and COVID-19: mechanistic insights from adipose tissue
L Yu, X Zhang, S Ye, H Lian, H Wang… - The Journal of Clinical …, 2022 - academic.oup.com
… The antiviral immune response requires the innate immune system [including NK cells,
dendritic cells, monocytes, macrophages, natural killer T (NKT) cells] and the adaptive …
dendritic cells, monocytes, macrophages, natural killer T (NKT) cells] and the adaptive …
Microarrays: monitoring for transplant tolerance and mechanistic insights
V Zarkhin, MM Sarwal - Clinics in Laboratory Medicine, 2008 - Elsevier
… responses against the graft are suppressed but the immune … absence of any detectable
detrimental immune response and no … of tolerance with an immune response or deficit that has no …
detrimental immune response and no … of tolerance with an immune response or deficit that has no …
Invasive fungal infections in the immunocompromised host: mechanistic insights in an era of changing immunotherapeutics
CP Eades, DPH Armstrong-James - Medical mycology, 2019 - academic.oup.com
… between intracellular signaling pathways and the immune response to human pathogens,
including clinically important fungi. Given that mechanistic therapeutics are likely to play an …
including clinically important fungi. Given that mechanistic therapeutics are likely to play an …
Immunomodulatory effects of a concoction of natural bioactive compounds—mechanistic insights
V Gangwar, A Garg, K Lomore, K Korla, SS Bhat… - Biomedicines, 2021 - mdpi.com
… have been studied for their efficacy and mechanism of action; however, their systemic … on
the molecular pathways involved in the immune response against various disease conditions [3]…
the molecular pathways involved in the immune response against various disease conditions [3]…
Mechanistic insights on hyperthermic intraperitoneal chemotherapy in ovarian cancer
OG Huffman, DB Chau, AI Dinicu, R DeBernardo… - Cancers, 2023 - mdpi.com
… The present review aims to provide insight into the mechanistic benefit of HIPEC treatment
with a focus on how hyperthermia activates the immune response, induces DNA damage, …
with a focus on how hyperthermia activates the immune response, induces DNA damage, …
Emerging mechanistic insights into the regulation of specialized metabolism in plants
… However, the question of how and when the balance between core and specialized metabolism
is altered (for instance, during immune responses) remains unresolved. Several lines of …
is altered (for instance, during immune responses) remains unresolved. Several lines of …
Mechanistic insights into SARS-CoV-2 epidemic via revealing the features of SARS-CoV-2 coding proteins and host responses upon its infection
… Taken together, our study provides a mechanistic insight into SARS-CoV-2 … response
to viral infections. However, excessive immune responses can cause pathological immune …
to viral infections. However, excessive immune responses can cause pathological immune …
Ammonia toxicity in the mud crab (Scylla paramamosain): The mechanistic insight from physiology to transcriptome analysis
CH Cheng, HL Ma, YL Su, YQ Deng, J Feng… - Ecotoxicology and …, 2019 - Elsevier
… To examine the reliability of the RNA-Seq results, ten candidate genes related to oxidative
stress and immune responses were selected for validation by qRT-PCR. Primers were …
stress and immune responses were selected for validation by qRT-PCR. Primers were …
Protumor activities of the immune response: insights in the mechanisms of immunological shift, oncotraining, and oncopromotion
GK Chimal-Ramírez, NA Espinoza-Sánchez… - Journal of …, 2013 - Wiley Online Library
… tumor cells or through a direct mechanism of capture from living tumor cells… immune responses.
Tumor-derived antigens presented to B and T lymphocytes trigger high-affinity responses …
Tumor-derived antigens presented to B and T lymphocytes trigger high-affinity responses …
Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models
F Martin, A Sewer, M Talikka, Y Xiang, J Hoeng… - BMC …, 2014 - Springer
… However, this approach often fails to provide mechanistic insights into the underlying
biology. During recent years, researchers addressed the complexity of such data by evaluating …
biology. During recent years, researchers addressed the complexity of such data by evaluating …