… prostate carcinoma cell line RM1 to generate a bone metastatic model of prostate cancer. …
cells followed by isolation of cells from bone tumors has yielded a cell line with strong bone-…

… Second, B6CaP metastasizes in an immune-competent mouse, making it possible for …
complexity of skeletal metastasis of prostate cancer in an immune competent environment. …

… , immunocompetent mouse model of bone metastasis and CIBP. The B6 Hi-Myc transgenic
mouse model of prostate cancer expresses the oncogene Myc in prostate epithelium and is …

… model of prostate cancer in the immunocompetent mouse that … Bone metastasis was not
detected by gross inspection nor … Bone metastasis in transgenic models of prostate cancer is …

… To visualize the proliferation of metastatic prostate cancer by bioluminescent technology,
PC-3, an established human prostate cancer cell line derived from a bone metastasis, was …

… Moreover, these lesions form in immunocompetent mice, which is a unique advantage
over the other models discussed in this review. There has been a wide variety of transgenic …

… as the bone. It is still not clear why rodent prostate cancer does not metastasize to the bone.
Further studies are needed to create a mouse model of prostate cancer with bone metastasis…

… is an immunomodulatory malignancy, much could be gained by studying prostate cancer in
immunocompetent mice. Additionally, in transgenic models, the expression of specific genes …

… observed in patients with metastatic prostate cancer. In the current study, we refine an
immunocompetent mouse model of prostate cancer induced bone pain involving orthotopic …

… Here we describe a new mouse model of PCa bone metastases, which shares important …
many metastatic prostate cancer patients. This model utilizes the Myc-CaP prostate cancer cell …