… Animal models of bone metastatic prostate cancer are necessary for understanding disease
… prostate carcinoma cell line RM1 to generate a bone metastatic model of prostate cancer. …

… A goal of the present study was to establish an orthotopic therapeutic model of prostate
cancer in the immunocompetent mouse that would provide an animal model to evaluate …

… in an immune-competent mouse, making it possible for researchers to study tumor-immune …
complexity of skeletal metastasis of prostate cancer in an immune competent environment. …

… in Pten -/- mouse models [10-12]. … mouse model was established using mouse prostate
cancer MPC3 cell line and that IL-17 promoted metastasis in this mouse model of prostate cancer…

… Utilizing the non-invasive and sensitive aspects of the luciferase/luciferin bioluminescence
system, we sought to generate a murine model for metastatic prostate cancer that mimicked …

… In this study, we established an immunocompetent prostate cancer bone pain model that
induced bone morphological changes and mirrored symptoms typically reported by patients …

… mouse prostate cancer MPC3-luc cells with Th17-polarized mouse splenocytes in the prostate
of immunocompetent … growth, however, metastasis (mainly to the pelvic lymph nodes) was …

… (IFN)-β, in an immunocompetent mouse model of prostate cancer lung metastasis. A
recombinant adeno-associated virus (rAAV) encoding mouse IFN-β was constructed and initially …

… one to do so in immunocompetent mice, an advantage shared with transgenic mice.
Modifications of the mouse prostate reconstitution model has produced bone metastases at a rate of …

… no longer be termed as mouse models; instead, they should be regarded as an intermediate
step between cell cultures and immunocompetent mouse cancer models and could be …