The sympathetic innervation of the mammalian cornea is thought to play an important role in
the regulation of epithelial ion transport, mitogenesis, and wound healing following corneal
injuries. Anatomically, the three‐dimensional organization and relative density of corneal
sympathetic innervation in many species remains inadequately described. In the present
study, the sympathetic innervation of five different mammals (guinea pig, rat, mouse,
hamster, and human) was studied in corneas sectioned parallel to the main axis of fiber …

The enzyme tyrosine hydroxylase (TH) catalyzes the rate-limiting step in the biosynthesis of
catecholamines in dopaminergic and noradrenergic neurons of the brain, in sympathetic
ganglion cells, and in chromaffin cells of the adrenal medulla 1 A1. Whether TH is
associated within cells with specific subcellular organelles or exists in a soluble form in
cytoplasm has been debated 2, 4, 9, 1, 13. In neurons it has been proposed on biochemical
evidence that the enzyme is synthesized in the perikarya and transported by axonal flow into …