Immunomodulatory therapies in sepsis
WJ Kox, T Volk, SN Kox, HD Volk - Intensive care medicine, 2000 - Springer
… septic patients, targeted intervention may lead to more success in immunomodulation of
sepsis… detected in serum and body fluids of septic patients [4], although the complex network …
sepsis… detected in serum and body fluids of septic patients [4], although the complex network …
Immunomodulatory therapy for sepsis: an update
E Christaki, P Anyfanti, SM Opal - … review of anti-infective therapy, 2011 - Taylor & Francis
… and the underlying pathophysiological pathways of sepsis. The development of intensive …
therapy and surgical techniques have improved the overall medical care of the septic patient. …
therapy and surgical techniques have improved the overall medical care of the septic patient. …
Why immunomodulatory therapies have not worked in sepsis
E Abraham - Intensive care medicine, 1999 - search.proquest.com
… A number of immunomodulatory therapies aimed at decreasing the dysregulated
inflammatory response have been examined in patients with sepsis (Table 1). Despite initially …
inflammatory response have been examined in patients with sepsis (Table 1). Despite initially …
New perspectives on immunomodulatory therapy for bacteraemia and sepsis
SM Opal - International Journal of Antimicrobial Agents, 2010 - Elsevier
… in septic patients during … immunomodulatory agents in sepsis will necessitate a personalised
medicine approach to treat each patient at the appropriate time and with the optimal therapy…
medicine approach to treat each patient at the appropriate time and with the optimal therapy…
Considering immunomodulatory therapies in the septic patient: should apoptosis be a potential therapeutic target?
A Oberholzer, C Oberholzer, RM Minter, LL Moldawer - Immunology Letters, 2001 - Elsevier
… anti-apoptotic therapies for septic patients at present, further exploration of this clinical
approach is clearly warranted. The successful treatment of the patient with sepsis will require …
approach is clearly warranted. The successful treatment of the patient with sepsis will require …
Immunomodulation in critically ill septic patients
GA Hassan, MA Azkol, SM Helal… - Menoufia Medical …, 2015 - menoufia-med-j.com
… of immunomodulatory therapies as well as current therapies trialed previously and potential
therapies … This study enrolled 64 patients with severe sepsis or septic shock who underwent …
therapies … This study enrolled 64 patients with severe sepsis or septic shock who underwent …
The new normal: immunomodulatory agents against sepsis immune suppression
NA Hutchins, J Unsinger, RS Hotchkiss… - Trends in molecular …, 2014 - cell.com
… The diminished capacity of septic patients to fight and eliminate infections often leads to the
development of secondary infections, mediated by otherwise weakly virulent or opportunistic …
development of secondary infections, mediated by otherwise weakly virulent or opportunistic …
Changes in immune function and immunomodulatory treatments of septic patients
Z Xu, A Liu, L Yang, B Zhang, F Zheng, J Zhang… - Clinical …, 2022 - Elsevier
… function of septic patients and some promising therapies for sepsis are summarized in this
review. Firstly, the innate immune system would be over-activated at the early stage of sepsis. …
review. Firstly, the innate immune system would be over-activated at the early stage of sepsis. …
Immunomodulatory therapies for sepsis: unexpected effects with macrolides
EJ Giamarellos-Bourboulis - International journal of antimicrobial agents, 2008 - Elsevier
… reduced to 3.78 among clarithromycin-treated patients. These results render new perspectives
for the future application of clarithromycin as an immunomodulatory therapy of sepsis. …
for the future application of clarithromycin as an immunomodulatory therapy of sepsis. …
Cytokines, sepsis and immunomodulation
RG Molloy, JA Mannick, ML Rodrick - British Journal of Surgery, 1993 - Wiley Online Library
… also reported a close correlation between the detection of TNF in the serum of patients
suffering from shock (septic and non-septic) and the risk of developing adult respiratory distress …
suffering from shock (septic and non-septic) and the risk of developing adult respiratory distress …
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