… pathogenesis of HBV liver disease (summarized in Figure 1). The study of the pathogenesis
of … support HBV infection. HBV can infect chimpanzees that only acquire a self-limiting acute …

… hepatitis B surface antigen (HBsAg) during the acute and chronic phase of hepatitis B virus
(HBV) infection … contribute to the immunopathogenesis of HBV persistent infection. Moreover, …

… responsible for viral clearance and disease pathogenesis during hepatitis B virus infection. It
… the clearance of circulating virus particles and the prevention of viral spread within the host …

… In general, a functional treatment is defined as a complete and long-lasting control of
hepatitis B viral infection which is mediated through inhibition or eradication of the infected cells. …

… fully eliminate HBV during natural infections and that T-cell responses, although they may
induce immunopathology, are required for control of acute HBV infection and contribute to the …

… viral clearance as well as liver disease. Here, we review our current knowledge on the
immunobiology and pathogenesis of HBV infection, … relevant source of hepatitis B surface antigen (…

… in the pathogenesis of hepatitis B; importantly, it can protect the liver from virus infections
by … However, IL-6 also has an important role in the induction of hepatitis, cirrhosis, and …

… in the pathogenesis and clinical outcome of HBV infection. In … virus-host interactions for the
pathogenesis of HBV infection … occurring viral variants for clinical disease, the role of virus-…

… Hepatitis B virus (HBV) is a typical non-cytopathic virus that can induce tissue damage of …
virus through the destruction of virus infected cells. Therefore, immune elimination of …

… are needed for viral clearance, whereas the cellular response also may be involved in disease
pathogenesis. Recent data support a noncytolytic mechanism of viral clearance mediated …