Immunoproteomic Analysis of Proteins Expressed by Two Related Pathogens, Burkholderia multivorans and Burkholderia cenocepacia, during Human Infection

M Shinoy, R Dennehy, L Coleman, S Carberry… - PLoS …, 2013 - journals.plos.org
Burkholderia cepacia complex (Bcc) is an opportunistic … Bcc are Burkholderia cenocepacia
and Burkholderia multivorans. … We have compared the immunoproteome of two strains each …

Characterization of the Burkholderia cenocepacia J2315 Surface-Exposed Immunoproteome

SA Sousa, AMM Seixas, M Mandal… - Vaccines, 2020 - mdpi.com
… More recently, the PspA-like protein BCAL2022 was also identified by immunoproteomics
in a study from our research group [19]. PspA-like proteins were previously shown to play a …

Identification of immunogenic proteins from Burkholderia cepacia secretome using proteomic analysis

V Mariappan, KM Vellasamy, JS Thimma, OH Hashim… - Vaccine, 2010 - Elsevier
Burkholderia cepacia is an opportunistic human pathogen associated … analysis to identify
immunogenic secretory proteins obtained from a clinical non-cystic fibrosis isolate of B. cepacia

New insights into the immunoproteome of B. cenocepacia J2315 using serum samples from cystic fibrosis patients

SA Sousa, P Soares-Castro, AMM Seixas… - New biotechnology, 2020 - Elsevier
… Bacteria of the Burkholderia cepacia complex (Bcc) are ubiquitous multidrug resistant
organisms … An immunoproteomics approach was used to identify Bcc proteins that stimulate the …

Surface-Exposed Protein Moieties of Burkholderia cenocepacia J2315 in Microaerophilic and Aerobic Conditions

AMM Seixas, C Silva, JMM Marques, P Mateus… - Vaccines, 2024 - mdpi.com
Burkholderia cepacia complex (Bcc) is a group of more than 26 related species, well known
… isolated from CF patients are Burkholderia cenocepacia and Burkholderia multivorans [4,5]. …

A Polyclonal Antibody against a Burkholderia cenocepacia OmpA-like Protein Strongly Impairs Pseudomonas aeruginosa and B. multivorans Virulence

AMM Seixas, SC Gomes, C Silva, LM Moreira… - Vaccines, 2024 - mdpi.com
… Pseudomonas aeruginosa and bacteria of the Burkholderia cepacia complex are among …
goat polyclonal antibody strongly inhibited Burkholderia cenocepacia to adhere and invade …

Linocin and OmpW are involved in attachment of the cystic fibrosis-associated pathogen Burkholderia cepacia complex to lung epithelial cells and protect mice …

S McClean, ME Healy, C Collins, S Carberry… - Infection and …, 2016 - Am Soc Microbiol
… Several other proteins identified as being involved in host cell attachment in this study
were also found to be immunogenic in our previously reported immunoproteomic analysis (36). …

The Burkholderia cenocepacia OmpA-like protein BCAL2958: identification, characterization, and detection of anti-BCAL2958 antibodies in serum from B. cepacia …

SA Sousa, M Morad, JR Feliciano, T Pita, S Nady… - AMB Express, 2016 - Springer
… Respiratory infections by bacteria of the Burkholderia cepacia complex (Bcc) remain an
important cause of morbidity and mortality among cystic fibrosis patients, highlighting the need …

Immunoinformatics approach for the deter-mination of antigenic epitope candidates against Burkholderia cenocepacia

Ç Yılmaz, AM Yılmaz, DA Tekdaş… - J Gene Engg Bio Res 3 …, 2021 - opastpublishers.com
… Besides known virulence factors, immunoproteomics approaches have been applied to identify
… Another study revealed that the immunoproteomic approach provided the identification of …

Immunization and Immunotherapy Approaches against Pseudomonas aeruginosa and Burkholderia cepacia Complex Infections

SA Sousa, AMM Seixas, JMM Marques, JH Leitão - Vaccines, 2021 - mdpi.com
… The Burkholderia cepacia complex (Bcc) is a group of Gram-… The Bcc encompasses
Burkholderia cepacia as the type … , Burkholderia cenocepacia and Burkholderia multivorans …