… This review will focus on investigating the immunotherapeutic efficacy of CpG ODN and
the enhancement in activity that can be achieved through the use of lipid nanoparticles as …

… Finally, the dimeric CpG class C, seem to combine effects of both previous CpG ODN types
… Intratumoral injection of a CpG oligonucleotide reverts resistance to PD-1 blockade by …

… The effects of CpG ODNs on human and mouse cells have been well studied in such
transfected cell lines, on the assumption that they mirror activity under physiological conditions. …

… ODN, and also discuss our own recent findings of the synergistic effects of CpG ODN and
Interleukin 21 (IL-21) on B chronic lymphocytic leukemia cells. For a more general review …

… expression in pDCs is sufficient to benefit from CpG as an adjuvant. These studies indicate
that the efficacy of CpG in cancer immunotherapy is dependent on cross-talk between pDCs …

… improving the efficacy of tumor immunotherapy. Treatment … CpG ODNs, treatment was
associated with a dramatic reduction in the frequency of infiltrating mMDSCs Citation[7]. This effect …

… of chemotherapy with CpG oligonucleotide and dendritic cell-based immunotherapy in the
… The coinjection of antigen-pulsed, mature dendritic cells and CpG oligonucleotides together …

… guide of the therapeutic potential and complexities of CpG ODN as an immunotherapeutic
adjuvant and the advanced drug delivery methods that can be used to enhance its efficacy. …

… Within the oligos tested, the strongest IFN-alpha induction is observed with … -concept studies,
we investigated the effect of adding the B-Class CpG ODN PF-3512676 to standard taxane/…

… CpG–ODN were conjugated to ragweed allergen in an allergic rhinitis immunotherapy study,
but only limited efficacy … Further study of CpG–ODNs for the treatment of asthma and other …