Immunotherapy of cancer with dendritic-cell-based vaccines

E Gilboa, SK Nair, HK Lyerly - Cancer Immunology, Immunotherapy, 1998 - Springer
… Hence the working hypothesis underlying the use of dendritic cells in tumor vaccination
is … from the tumor cell to the dendritic cell, and that direct loading of dendritic cells with the …

Dendritic cells in cancer immunotherapy

L Fong, EG Engleman - Annual review of immunology, 2000 - annualreviews.org
… Although currentdendritic cell–based vaccination methods … cancer suggest that
immunotherapeutic strategies that take advantageof the antigen presenting properties of dendritic

Cancer immunotherapy by dendritic cells

CJM Melief - Immunity, 2008 - cell.com
… in cancer tissue and draining lymph nodes usually carry an “immature” phenotype and that
myeloid-derived suppressor cells (… I will then discuss how DC-based immunotherapy can be …

Cancer immunotherapy via dendritic cells

K Palucka, J Banchereau - Nature Reviews Cancer, 2012 - nature.com
Cancer cells attract immature dendritic cells (DCs), possibly through chemokines such as
CCL20 or CXCL12. DCs can then be exposed to cancer-derived factors — for example, thymic …

Dendritic cells in cancer immunology and immunotherapy

SK Wculek, FJ Cueto, AM Mujal, I Melero… - Nature Reviews …, 2020 - nature.com
… Although dendritic cells (DCs) constitute a rare immune cell population within tumours and
lymphoid organs, these cells are central for the initiation of antigen-specific immunity and …

The use of dendritic cells in cancer immunotherapy

A Nencioni, F Grünebach, SM Schmidt… - Critical reviews in …, 2008 - Elsevier
cancer stem cells [3]. So, the question is now by which means we can improve immunotherapy
for cancer … Different immunotherapeutic strategies more or less directly target a leukocyte …

Dendritic cells and cancer immunotherapy

KJ Radford, KM Tullett, MH Lahoud - Current opinion in immunology, 2014 - Elsevier
Dendritic cells (DC) play an essential role in the induction and regulation of immune
responses, … Cancer immunotherapy via dendritic cells Nat Rev Cancer, 12 (2012), pp. 265-277 …

Dendritic cells in cancer immunotherapy

G Schuler - European journal of immunology, 2010 - Wiley Online Library
DC initiate and regulate T‐cell immunity and are thus the key to optimization of all types of
vaccines. Insights into DC biology offer many opportunities to enhance immunogenicity. In this …

The use of dendritic cells in cancer immunotherapy

G Schuler, B Schuler-Thurner, RM Steinman - Current opinion in …, 2003 - Elsevier
… A novel approach to vaccination against cancer is to exploit dendritic cells (DCs) as ‘nature’s
adjuvants’ and actively immunize cancer patients with a sample of their own DCs primed …

Dendritic cells and immunotherapy for cancer

DH Chang, MV Dhodapkar - International journal of hematology, 2003 - Springer
… Use of these cells in cancer immunotherapy has been bolstered by newer insights in DC …
Active immunization against cancer with dendritic cells: the near future. Int J Cancer. 2001;…