The impact of curcumin and its modified formulations on Alzheimer's disease

T Farkhondeh, S Samarghandian… - Journal of cellular …, 2019 - Wiley Online Library
Alzheimer's disease (AD) is a major health problem worldwide, with no effective treatment
approach. Curcumin is the … the protective effect of curcumin and its novel formulations in AD. …

[HTML][HTML] The effect of curcumin on cognition in Alzheimer's disease and healthy aging: A systematic review of pre-clinical and clinical studies

SD Voulgaropoulou, T Van Amelsvoort, J Prickaerts… - Brain research, 2019 - Elsevier
… respectively Male Sprague Dawley rats (N = 40; n = 8 in each group) Y-Maze, OFT, MWM
The modulating impact of curcumin on cognitive deficits after ventricular injection of amyloid-β1…

Curcumin structure-function, bioavailability, and efficacy in models of neuroinflammation and Alzheimer's disease

AN Begum, MR Jones, GP Lim, T Morihara… - … of Pharmacology and …, 2008 - ASPET
… we investigated the differential impacts of curcumin versus TC on … In the chronic model, we
investigated curcumin metabolism … the impact of the major and minor metabolites of curcumin, …

Use of curcumin in diagnosis, prevention, and treatment of Alzheimer's disease

M Chen, ZY Du, X Zheng, DL Li, RP Zhou… - Neural regeneration …, 2018 - journals.lww.com
diseases, and decrease the risk of Alzheimer's disease. The effect of curcumin on Alzheimer's
disease … , and therapeutic measures to control the impact of this devastating disease. …

The mechanisms of action of curcumin in Alzheimer's disease

M Tang, C Taghibiglou - Journal of Alzheimer's disease, 2017 - content.iospress.com
… The diverse array of the effects of curcumin and its disease modifying properties may
have a notable impact on the future of drug treatment for AD. AChE inhibitors and NMDA …

Examining the potential clinical value of curcumin in the prevention and diagnosis of Alzheimer's disease

KG Goozee, TM Shah, HR Sohrabi… - British Journal of …, 2016 - cambridge.org
… is renewing optimism concerning curcumin-based therapy. The aim … curcumin and modulation
of AD pathology, including in vitro and in vivo studies. We also review the use of curcumin

Neuroprotective properties of curcumin in Alzheimer's disease-merits and limitations

D Chin, P Huebbe, K Pallauf… - Current medicinal …, 2013 - ingentaconnect.com
… of curcumin, brain concentration of curcumin remains low. … curcumin possesses a relatively
low toxicity profile, curcumin … potential of curcumin, with emphasis on Alzheimer’s disease, …

Curcumin in Alzheimer's disease: Can we think to new strategies and perspectives for this molecule?

MM Serafini, M Catanzaro, M Rosini, M Racchi… - Pharmacological …, 2017 - Elsevier
… treatments and its hard impact on both healthcare workers and families. … Curcumin activities
in Alzheimer's disease. Mechanisms of action of curcumin related to Alzheimer’s disease

Protective effects of a natural product, curcumin, against amyloid β induced mitochondrial and synaptic toxicities in Alzheimer's disease

PH Reddy, M Manczak, X Yin… - Journal of …, 2016 - journals.sagepub.com
curcumin’— in Alzheimer's disease (AD)-like neurons. Although much research has been
done in AD, very little has been reported on the effects of curcumin … huge economic impact, and …

Curcumin in health and diseases: Alzheimer's disease and curcumin analogues, derivatives, and hybrids

E Chainoglou, D Hadjipavlou-Litina - International journal of molecular …, 2020 - mdpi.com
Curcumin, which is the principal component of Curcuma longa, has shown favorable effects
… of curcumin. This review summarizes bibliographical data from 2009 to 2019 on curcumin