Impact of weight on the efficacy and safety of direct-acting oral anticoagulants in patients with non-valvular atrial fibrillation: a meta-analysis

AH Malik, S Yandrapalli, S Shetty, WS Aronow… - EP …, 2020 - academic.oup.com
… This study sought to determine the impact of weight and body mass index (BMI) on the
safety and efficacy of direct-acting oral anticoagulants (DOACs) compared with warfarin in …

Effect of body weight on efficacy and safety of direct oral anticoagulants in the treatment of patients with acute venous thromboembolism: a meta-analysis of …

MND Di Minno, R Lupoli, A Di Minno… - Annals of …, 2015 - Taylor & Francis
… evaluating the impact of body weight on safety and efficacy of direct oral anticoagulants (DOACs)
as … The efficacy and safety of DOACs is comparable with that of VKA in different weight

[HTML][HTML] Association of body weight with efficacy and safety outcomes in phase III randomized controlled trials of direct oral anticoagulants: a systematic review and …

K Boonyawat, F Caron, A Li… - Journal of Thrombosis …, 2017 - Elsevier
oral anticoagulant (DOAC)‐treated patients about safety and efficacy in extremes of body
weight… The aims of this systematic review were to investigate the association of body weight

Evaluation of safety and efficacy outcomes of direct oral anticoagulants versus warfarin in normal and extreme body weights for the treatment of atrial fibrillation or …

AR Novak, C Shakowski, TC Trujillo, GC Wright… - Journal of Thrombosis …, 2022 - Springer
… of body weight remains controversial. This study aimed to measure the impact of DOACs
compared to warfarin on safety and efficacy outcomes in extreme body weight patients. This …

Direct oral anticoagulant concentrations in obese and high body weight patients: a cohort study

AC Martin, W Thomas, Z Mahir… - Thrombosis and …, 2021 - thieme-connect.com
oral anticoagulant (DOAC) concentrations and ranges measured in our cohort and values
expected in unselected body weight … Therefore, the clinical impact and consequences on …

The non-vitamin K antagonist oral anticoagulants (NOACs) and extremes of body weight—a systematic literature review

R De Caterina, GYH Lip - Clinical Research in Cardiology, 2017 - Springer
… , the impact of the protocol-specified 50% dose reductions applied to patients with body weight
≤60 … in this population, and assessed the impact of protocol-specified dose reductions on …

Direct oral anticoagulants in patients with nonvalvular atrial fibrillation and low body weight

SR Lee, EK Choi, CS Park, KD Han, JH Jung… - Journal of the American …, 2019 - jacc.org
… From a total of 135,939 new users of oral anticoagulants (OACs) since January 2014, 7,576
warfarin users and 14,103 direct oral anticoagulant (DOAC) users were included in this study…

Direct oral anticoagulants in obesity: an updated literature review

J Sebaaly, D Kelley - Annals of Pharmacotherapy, 2020 - journals.sagepub.com
… , direct-acting oral anticoagulants (DOACs) have … impact of high BW/BMI on renal clearance
because of the aforementioned factors as well as the debate on the most appropriate weight

Effects of body mass index on the safety and effectiveness of direct oral anticoagulants: a retrospective review

J Netley, K Howard, W Wilson - Journal of thrombosis and thrombolysis, 2019 - Springer
… and Haemostasis recommends avoiding the use of direct oral anticoagulants (DOACs) in
patients with a body mass index (BMI) greater than 40 kg/m 2 or weight greater than 120 kg. …

Efficacy and safety of direct oral anticoagulants for atrial fibrillation across body mass index categories

RM Kaplan, Y Tanaka, RS Passman… - Journal of the …, 2020 - Am Heart Assoc
… As prevalence of both obesity and AF increase, the issue of managing anticoagulation in
patients with AF and elevated body weight has become even more essential to address in …