… due to the failure of alternative drug discovery methods to deliver many lead compounds …
drug discovery methods, and also to keep pace with the ongoing changes in the drug discovery …

… Use of a uniform definition for PDD helps to illuminate the impact of PDD on modern drug
discovery 1,6 , and underlines the importance and impact of empirical drug discovery …

… for drug discovery and development. We define how this blossoming field has already
impacted the pharmaceutical industry and describe how it can further enhance the drug discovery …

… from FBDD have permeated and enhanced drug discovery efforts. … the impact of FBDD
goes further: the fundamental principles of FBDD have changed the strategies of drug discovery …

… Non-profit organizations (NPO) play an increasingly important role in drug discovery and …
Drug discovery in the field of neglected diseases is fraught with complexities since, in many …

… drug) and to initiate a drug discovery program were limited to thefollowing: The target is
highly expressed in a human cell of interest, theosteoclast; the target is selectively expressed in …

… The process of drug discovery encompasses a period of intense R&D effort that typically
spans 13–15 yr, and involves: (i) search for a target to start a programme or project, (ii) lead …

… Natural products in drug discovery: impacts and opportunities—an assessment. In Bioactive
Natural Products: Opportunities and Challenges in Medicinal Chemistry; World Scientific …

… to the process of drug development and discovery, the current … scientists over the course of
drug discovery and development. … Budget cuts have impacted clinical research as well as pre-…

… changes provide unprecedented opportunities for many … that have had an extraordinary
impact; in terms of promoting … will be needed to ensure continuation of new drug discovery. …