Impaired expression of GABA transporters in the human Alzheimer's disease hippocampus, subiculum, entorhinal cortex and superior temporal gyrus

TE Fuhrer, TH Palpagama, HJ Waldvogel, BJL Synek… - Neuroscience, 2017 - Elsevier
… , entorhinal cortex and superior temporal gyrus. We found a significant increase in BGT-1
expression … In AD there was a significant decrease in GAT-1 expression in the entorhinal cortex

Entorhinal cortex dysfunction in Alzheimer's disease

KM Igarashi - Trends in neurosciences, 2023 - cell.com
… The entorhinal cortex (EC) is the brain region that often exhibits the earliest … that impaired
neuronal activity in the EC precedes neurodegeneration. This implies that memory impairments

Entorhinal cortex and consolidated memory

K Takehara-Nishiuchi - Neuroscience research, 2014 - Elsevier
… The lesion made before the training does not impair the acquisition of spatial memory or
its expression one day later. In contrast, the lesion significantly impairs memory …

Cognitive decline is associated with reduced reelin expression in the entorhinal cortex of aged rats

AM Stranahan, RP Haberman, M Gallagher - Cerebral Cortex, 2011 - academic.oup.com
… RNA expression in the lateral entorhinal cortex of aged rats that are cognitively impaired
The lateral entorhinal cortex of aged rats with cognitive impairment also exhibited changes …

Impaired neuronal plasticity in transgenic mice expressing human apolipoprotein E4 compared to E3 in a model of entorhinal cortex lesion

F White, JAR Nicoll, AD Roses, K Horsburgh - Neurobiology of disease, 2001 - Elsevier
… same line of transgenic mice as employed in this study revealed impaired neuronal sprouting
in APOEε4 expressing slices when compared to those expressing ε3 (Teter et al., 1999). …

Hippocampus and entorhinal cortex in mild cognitive impairment and early AD

C Pennanen, M Kivipelto, S Tuomainen… - Neurobiology of …, 2004 - Elsevier
… Based on MRI-derived volumes, we studied the hippocampus and entorhinal cortex (ERC)
in 59 controls, 65 individuals with mild cognitive impairment (MCI) and 48 patients with AD. …

Astrocyte control of the entorhinal cortex‐dentate gyrus circuit: Relevance to cognitive processing and impairment in pathology

MA Di Castro, A Volterra - Glia, 2022 - Wiley Online Library
entorhinal cortex conveys spatial information about the context received from the perirhinal
cortex, whereas the lateral entorhinal cortex … from the parahippocampal cortex. PP axons …

Focal expression of mutated tau in entorhinal cortex neurons of rats impairs spatial working memory

JJ Ramirez, WE Poulton, E Knelson, C Barton… - Behavioural brain …, 2011 - Elsevier
… the dentate molecular layer supports the hypothesis that the behavioral impairment resulting
from P301L tau expression in entorhinal cortex is not due to a substantial denervation of …

Lateral entorhinal cortex dysfunction in amnestic mild cognitive impairment

TT Tran, CL Speck, M Gallagher, A Bakker - Neurobiology of aging, 2022 - Elsevier
… Furthermore, reduced expression of reelin in memory-impaired aged rodents was
observed in conjunction with increased tau phosphorylation, also localized to the lateral …

Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease

UA Khan, L Liu, FA Provenzano, DE Berman… - Nature …, 2014 - nature.com
impairment and, ultimately, dementia 13 . To test the hypothesis of differential dysfunction in
the entorhinal cortex… APP or tau expression in the left versus right entorhinal cortex of control …