Butyrate inhibits inflammatory responses through NFκB inhibition: implications for Crohn's disease
JP Segain, DR De La Blétiere, A Bourreille, V Leray… - Gut, 2000 - gut.bmj.com
… key factors in the pathogenesis of Crohn's disease (CD). … patients. As butyrate enemas may
be beneficial in treating colonic inflammation, we investigated if butyrate promotes this effect …
be beneficial in treating colonic inflammation, we investigated if butyrate promotes this effect …
Defective acute inflammation in Crohn's disease: a clinical investigation
… reaction and produce a secondary chronic inflammation. We undertook to examine acute
inflammatory responses in Crohn's disease … , we investigated the consequences of trauma to …
inflammatory responses in Crohn's disease … , we investigated the consequences of trauma to …
Bacteria in Crohn's disease: mechanisms of inflammation and therapeutic implications
RB Sartor - Journal of clinical gastroenterology, 2007 - journals.lww.com
… Transient infection with pathogenic organisms could serve as environmental triggers to
initiate inflammatory responses that are perpetuated in susceptible hosts by commensal …
initiate inflammatory responses that are perpetuated in susceptible hosts by commensal …
Crohn's disease: an immune deficiency state
… the downstream consequences of chronic inflammation. The … -infectious inflammatory bowel
disease arising in patients with … the innate inflammatory response in Crohn’s disease in the …
disease arising in patients with … the innate inflammatory response in Crohn’s disease in the …
Crohn's disease
F Shanahan - The Lancet, 2002 - thelancet.com
… forms of inflammatory bowel disease, with an adverse effect on … In Crohn's disease, mucosal
T cells are resistant to apoptosis… of T cells and perpetuation of the inflammatory response. …
T cells are resistant to apoptosis… of T cells and perpetuation of the inflammatory response. …
Managing immunogenic responses to infliximab: treatment implications for patients with Crohn's disease
PD Han, RD Cohen - Drugs, 2004 - Springer
… In an analysis of 129 patients treated with infliximab for … Crohn’s disease, we described
infusion reactions as complicating 5–13% of infusions.[10] In 100 patients with Crohn’s disease, …
infusion reactions as complicating 5–13% of infusions.[10] In 100 patients with Crohn’s disease, …
[HTML][HTML] Nutritional modulation of the inflammatory response in inflammatory bowel disease-from the molecular to the integrative to the clinical
GE Wild, L Drozdowski, C Tartaglia… - World journal of …, 2007 - ncbi.nlm.nih.gov
… provide important supportive therapy for IBD patients, but in adults … of IBD patients, and
recent studies have stressed the role of PPAR on NFκB activity on the potential beneficial effect of …
recent studies have stressed the role of PPAR on NFκB activity on the potential beneficial effect of …
[HTML][HTML] Current view of the immunopathogenesis in inflammatory bowel disease and its implications for therapy
MI Torres, A Rios - World journal of gastroenterology: WJG, 2008 - ncbi.nlm.nih.gov
… antigen presentation, with maintenance of intestinal immuno-regulation and tolerance to
components of intestinal flora, controlling the inflammatory responses to intestinal antigens[26]. …
components of intestinal flora, controlling the inflammatory responses to intestinal antigens[26]. …
Modulation of inflammation by autophagy: consequences for Crohn's disease
TS Plantinga, LAB Joosten, JWM van der Meer… - Current opinion in …, 2012 - Elsevier
… A major effect of autophagy in inflammation is modulation of the production of the … inflammatory
responses, but also reshape our insights into the pathogenesis of inflammatory diseases. …
responses, but also reshape our insights into the pathogenesis of inflammatory diseases. …
The immune response in inflammatory bowel disease
SJ Brown, L Mayer - Official journal of the American College of …, 2007 - journals.lww.com
… IBD. In some individuals, the overt inflammatory response may be an appropriate response
… are important considerations. A combination of oral plus topical therapy may also maximize …
… are important considerations. A combination of oral plus topical therapy may also maximize …
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