As the field begins to test the concept of a "preclinical" stage of neurodegenerative disease,
when the pathophysiological process has begun in the brain, but clinical symptoms are not …

… of AD and how they have impacted the evolution of criteria for defining the disease; (3)
current challenges including the impact of multimorbidity, and (4) implications for prevention. …

… In Alzheimer's Disease amyloid-p protein on its way to brain … be effective in preventing
Alzheimer's Disease. Nevertheless, … and progression of Alzheimer's Disease as well as of other …

Alzheimer’s disease (AD) is a neurodegenerative disease with a complex and progressive
pathological phenotype characterized first by hypometabolism and impaired mitochondrial …

The aim of this review is to propose a Unified Theory of Alzheimer’s disease (UTAD) that
integrates all key behavioural, genetic and environmental risk factors in a causal chain of …

… Are these findings of E 2 regulation of mitochondrial function and enhancement of aerobic
glycolysis relevant to Alzheimer disease risk? The role of mitochondria in health and disease …

… by herpesviruses might be closely linked to Alzheimer's disease (AD). Pathological hallmarks
of … of AD, and discuss the implications for future prevention and treatment of the disease. …

… We investigated the potential implications of PEs in Alzheimer's disease prevention trials
using placebo arm data from the Alzheimer's Disease Cooperative Study donepezil/vitamin E …

… on the disease process. Based in part on this evidence, the Alzheimer's Disease Cooperative
… Next, we will discuss potential implications regarding the recent evidence showing the …

Alzheimer's disease (AD) is one of the most common dementing disorders and has profound
medical and social consequences. The initiating molecular event is unknown, and its …