The synaptic vesicle protein 2A interacts with key pathogenic factors in Alzheimer's disease: implications for treatment
Y Kong, L Huang, W Li, X Liu, Y Zhou, C Liu… - Frontiers in cell and …, 2021 - frontiersin.org
… Synaptic vesicle protein 2A (SV2A) is an indispensable vesicular protein specifically … such
as amyloid precursor protein (APP), β-amyloid (Aβ), and Tau protein is not thoroughly clear. In …
as amyloid precursor protein (APP), β-amyloid (Aβ), and Tau protein is not thoroughly clear. In …
Vesicle permeabilization by protofibrillar α-synuclein: implications for the pathogenesis and treatment of Parkinson's disease
MJ Volles, SJ Lee, JC Rochet, MD Shtilerman… - Biochemistry, 2001 - ACS Publications
… Protein binding to vesicles was monitored on an upgraded BIAcore 1000 instrument at 2 μL/…
Subsequently, the protein-containing buffer was replaced with HBS, and protein dissociation …
Subsequently, the protein-containing buffer was replaced with HBS, and protein dissociation …
Importance of vesicle proteins in the diagnosis and treatment of neuroendocrine tumors
O Nilsson, AML JAKOBSEN, L Kölby… - Annals of the New …, 2004 - Wiley Online Library
… prognostic and therapeutic implications. Besides surgical and medical … of vesicle proteins
in neuroendocrine tumor, and the importance of vesicle proteins in diagnosis and treatment of …
in neuroendocrine tumor, and the importance of vesicle proteins in diagnosis and treatment of …
The emerging role of extracellular vesicle‐mediated drug resistance in cancers: Implications in advanced prostate cancer
C Soekmadji, CC Nelson - BioMed research international, 2015 - Wiley Online Library
… Recently it has been shown that the presence of multidrug resistance proteins such as Pgp‐…
uptake of drugs in vesicles and thus limit the bioavailability of drugs to treat cancer cells. In …
uptake of drugs in vesicles and thus limit the bioavailability of drugs to treat cancer cells. In …
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- implications for treatment vesicle protein
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- synaptic vesicle membrane proteins
Synaptic vesicle membrane proteins interact to form a multimeric complex.
MK Bennett, N Calakos, T Kreiner… - The Journal of cell …, 1992 - rupress.org
… We have found that a large complex including five ofthe six vesicle proteins is preferentially
… between synaptic vesicle proteins we observe have a number of implications with regard to …
… between synaptic vesicle proteins we observe have a number of implications with regard to …
Methylphenidate‐Induced Alterations in Synaptic Vesicle Trafficking and Activity: Functional Consequences and Therapeutic Implications
TJ Volz, SJ Farnsworth, GR Hanson… - Annals of the New …, 2008 - Wiley Online Library
… MPD also indirectly affects DA transport by the vesicular monoamine transporter-2 (VMAT-2),
a protein that transports cytoplasmic DA into synaptic vesicles inside neuronal cells for …
a protein that transports cytoplasmic DA into synaptic vesicles inside neuronal cells for …
Synaptic vesicle-recycling machinery components as potential therapeutic targets
YC Li, ET Kavalali - Pharmacological reviews, 2017 - ASPET
… vesicle cycle—such as exocytosis and endocytosis—require formation and disassembly of
protein … subtle alterations in synaptic vesicle cycle-associated proteins directly or indirectly …
protein … subtle alterations in synaptic vesicle cycle-associated proteins directly or indirectly …
Exosome-and extracellular vesicle-based approaches for the treatment of lysosomal storage disorders
B Lu, J Ku, R Flojo, C Olson, D Bengford… - Advanced Drug Delivery …, 2022 - Elsevier
… course has important implications in disease management. In particular, early diagnosis
and prompt treatments of specific LSDs may help to limit the severity of the condition [8]. …
and prompt treatments of specific LSDs may help to limit the severity of the condition [8]. …
Extracellular vesicles in cancer—implications for future improvements in cancer care
… ), the GTPase RAS-related protein RAB7A, and members of the … protein receptor (SNARE)
complex, including vesicle-associated membrane protein 7 (VAMP7), which mediate vesicle …
complex, including vesicle-associated membrane protein 7 (VAMP7), which mediate vesicle …
Alterations in cellular processes involving vesicular trafficking and implications in drug delivery
S Muro - Biomimetics, 2018 - mdpi.com
… vesicular transport may arise from the molecular defects underlying the pathological syndrome
which we aim to treat, the … on the use of vesicular transport for drug delivery applications. …
which we aim to treat, the … on the use of vesicular transport for drug delivery applications. …