… ’ laboratory on the therapeutic importance of Rho-kinase … in our knowledge of the therapeutic
importance of Rho-kinase … the translational research on the therapeutic importance of Rho-…

… Our findings suggest that Rho-kinase/CyPA signaling pathway is a novel therapeutic target
for aortic aneurysm. All these data are a proof of concept that both Rho-kinase and CyPA …

… Identification and exploration of these targets are important for … of therapeutic targets and
to investigate the characteristics of these targets for providing useful clues to search new targets…

… Therefore, the inhibition of NF-KB can be a therapeutic target for the prevention or treatment
of undesiredbiologic responses caused by the activation of NF-KB. The objectives of this …

… This further highlights the key role of BCR-ABL signaling in oncogenesis and affirms the
position of BCR-ABL as the central therapeutic target in Ph + CML. The efficacy of novel BCR-…

… as an important therapeutic target for many of the integrin, angiogenesis, matrix and vascular
permeability related clinical conditions. A recent report indicating that interference with PAK …

… -based anticancer therapy. The role of osteopontin in promoting cancer progression is the
subject of in depth investigation and thus targeting osteopontin might be a suitable therapeutic …

… /mTOR pathway may represent an important therapeutic target for the treatment of HCC
among … Therefore, these studies suggested the possible use of PTEN as a target in therapeutic …

… This study demonstrated that mitochondrial function exerts important functions relevant to
melanoma cell survival and death, and that the drug Elesclomol targets a pertinent cellular …

… regarding breast cancer therapy. Aromatase provided one of the first molecular targets for
rational … Comprehensive studies of aromatase demonstrated the importance of extraglandular …