[HTML][HTML] Management of colorectal cancer

S Stintzing - F1000prime reports, 2014 - ncbi.nlm.nih.gov
… of 6 months has been reported, which was increased to 12 months by treatment with 5-FU …
combination with leucovorin, decreased toxicity and increased efficacy of 5-FU treatment. The …

Systemic therapy for metastatic colorectal cancer: current options, current evidence

H Kelly, RM Goldberg - Journal of Clinical Oncology, 2005 - ascopubs.org
… in colorectal cancer treatment. From the late 1950s until very recently, fluorouracil (FU) was
the only drug approved for the treatment of colorectal cancer. … toxicity and increased efficacy, …

[HTML][HTML] Immunotherapy of colorectal cancer: Challenges for therapeutic efficacy

D Ciardiello, PP Vitiello, C Cardone, G Martini… - Cancer treatment …, 2019 - Elsevier
… immunogenicity in metastatic colorectal cancer is needed in … in the context of metastatic
colorectal cancer. We summarize the … in an increased risk of developing several types of cancer, …

A systematic review of FOLFOXIRI chemotherapy for the first‐line treatment of metastatic colorectal cancer: improved efficacy at the cost of increased toxicity

F Montagnani, A Chiriatti, G Turrisi… - Colorectal …, 2011 - Wiley Online Library
… failed to demonstrate significant differences of efficacy. Minor differences were … efficacy and
toxicity of the first-line treatment with FOLFOXIRI in metastatic unresectable colorectal cancer

Efficacy and safety of bevacizumab in metastatic colorectal cancer: pooled analysis from seven randomized controlled trials

HI Hurwitz, NC Tebbutt, F Kabbinavar… - The …, 2013 - academic.oup.com
… to chemotherapy was associated with statistically significant increases in overall survival (OS;
HR… perforations, and thromboembolic events were increased with bevacizumab treatment. …

Systemic treatment of colorectal cancer

BM Wolpin, RJ Mayer - Gastroenterology, 2008 - Elsevier
colorectal cancer and increasing cure rates among those with resectable disease. … Oaks,
CA), have definitively shown efficacy in colorectal cancer (Table 3). Although small molecule …

[HTML][HTML] Treatment in advanced colorectal cancer: what, when and how?

I Chau, D Cunningham - British journal of cancer, 2009 - nature.com
… with CAPIRI that compromised CAPIRI's efficacy and increased its toxicity. A further large …
Further development in alterative dosing schedule of CAPIRI could provide a better efficacy

The effectiveness of a self-efficacy-enhancing intervention for Chinese patients with colorectal cancer: a randomized controlled trial with 6-month follow up

M Zhang, SW Chan, L You, Y Wen, L Peng… - International journal of …, 2014 - Elsevier
… in increasing self-efficacy and quality of life, and decreasing symptom distress in
colorectal cancer … the hypothesis that colorectal cancer patients who received self-efficacy-enhancing …

An update of efficacy and safety of cetuximab in metastatic colorectal cancer: a narrative review

G Fornasier, S Francescon, P Baldo - Advances in therapy, 2018 - Springer
… The addition of EGFR MAb to either chemotherapy or best supportive care improves
progression-free survival, overall survival and tumour response rate, but may increase toxicity in …

Alpha-interferon does not increase the efficacy of 5-fluorouracil in advanced colorectal cancer

MAG in Cancer - British Journal of Cancer, 2001 - ncbi.nlm.nih.gov
… We conclude that α-IFN does not increase the efficacy of 5FU … + LV, for patients with advanced
colorectal cancer. © 2001 … not increase the efficacy of 5FU in advanced colorectal cancer