… derived from the anatomic regions of the oral and nasal cavity and also of the pharynx
and larynx. Oral cavity SCC (OCSCC) demonstrates an increasing rate due to viral –related (High …

… We show here that the increased mutation burden in larynx SCC noted by others is a direct
result of tobacco smoke-associated signature 4 mutation load (Fig. 1, Supplementary Figs. …

… cell lines with p53 gene mutations was observed. Otherwise, … Our results both in oral cavity
carcinomas and previously in … some earlier studies showing increased radioresistance of p53-…

… mutation prevalence of the TERT promoter in oral cavity SCC, we extracted total DNA from
201 oral cavity … C228T and C250T mutations in the TERT promoter significantly increased in …

… This investigation aims to review the known genetic mutations associated with oral cavity …
this same increase in incidence has not been observed among other subsites of the oral cavity, …

… strain to colonize the oral cavity correlated with its production of … Also reported was a mutant
of strain JH1001, called JH1005, … This mutant was found to colonize the oral cavity of rodents …

… Although there is a slight increase in cancer risk resulting … In recent years, an increased
incidence of oral cavity cancers… incidence of p53 mutations in oral cavity premalignant lesions is …

… Overall, 645 somatic mtDNA mutations were identified and 91 of these mutations … mutations.
Individuals with the TP53 R allele had a higher frequency of pathogenic somatic mutation …

… Oral cavity squamous cell carcinoma (OC‐SCC) is the most common malignancy of the …
(OP‐SCC), with a marked increase in lesions related to human papillomavirus infection. This …

… , TERT promoter mutations were associated with an increased risk of LRF, but not distant
failure or OS. Of note, both C228A/T and C250T mutations were associated with increased risk …