Molecular mechanisms responsible for increased vulnerability of the ageing oocyte to oxidative damage
BP Mihalas, KA Redgrove… - Oxidative medicine …, 2017 - Wiley Online Library
… of oxidative damage in the maternally aged oocyte likely results from the convergence of an
increase in … capacity of the oocyte to mitigate oxidative damage. We also urge further basic …
increase in … capacity of the oocyte to mitigate oxidative damage. We also urge further basic …
Selective vulnerability to kainate‐induced oxidative damage in different rat brain regions
E Candelario‐Jalil, SM Al‐Dalain… - Journal of Applied …, 2001 - Wiley Online Library
… Our goal in this study was to determine the pattern of oxidative damage induced by
systemically administered KA in selected areas of the rat brain at two different sampling times. …
systemically administered KA in selected areas of the rat brain at two different sampling times. …
Pathways of oxidative damage
JA Imlay - Annual Reviews in Microbiology, 2003 - annualreviews.org
… Conversely, the vulnerability ofbacteria to DNA damage is increased by mutations that
upregulate iron importand thereby elevate intracellular iron levels(88). The iron that catalyzes …
upregulate iron importand thereby elevate intracellular iron levels(88). The iron that catalyzes …
Selective neuronal vulnerability to oxidative stress in the brain
X Wang, EK Michaelis - Frontiers in aging neuroscience, 2010 - frontiersin.org
… of some neurons is partially underlied by deficient DNA damage repair. As described earlier…
in a region that is vulnerable to OS, the repair of DNA damage was increased initially but did …
in a region that is vulnerable to OS, the repair of DNA damage was increased initially but did …
Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia
SE Browne, AC Bowling, U Macgarvey… - Annals of Neurology …, 1997 - Wiley Online Library
… of energetic defects and oxidative damage in the disease … evidence of impaired oxidative
phosphorylation enzyme activities … We also measured levels of the oxidative damage product 8-…
phosphorylation enzyme activities … We also measured levels of the oxidative damage product 8-…
[HTML][HTML] Increasing vulnerability of astrocytes to oxidative injury with age despite constant antioxidant defenses
MC Papadopoulos, IL Koumenis, TY Yuan, RG Giffard - Neuroscience, 1997 - Elsevier
… reflects oxidative damage since it is significantly reduced by either trolox or dimethylthiourea,
and may, in common with the other injury paradigms, in part reflect the increased oxidative …
and may, in common with the other injury paradigms, in part reflect the increased oxidative …
Oligodendroglia are particularly vulnerable to oxidative damage after neurotrauma in vivo
MK Giacci, CA Bartlett, NM Smith, KS Iyer… - Journal of …, 2018 - Soc Neuroscience
… vulnerable to this damage remain to be elucidated. Here we use powerful NanoSIMS techniques
to show increased oxidative damage … are the most vulnerable to DNA oxidation. Further …
to show increased oxidative damage … are the most vulnerable to DNA oxidation. Further …
Increase in vulnerability to oxidative damage in cholesterol-modified erythrocytes exposed to t-BuOOH
A López-Revuelta, JI Sánchez-Gallego… - … et Biophysica Acta (BBA …, 2005 - Elsevier
… and membrane susceptibility to oxidative damage induced by … increased ROS production,
with almost complete oxidation of … Fluorescence anisotropy studies showed an increase in the …
with almost complete oxidation of … Fluorescence anisotropy studies showed an increase in the …
How important is oxidative damage? Lessons from Alzheimer's disease
… Therefore, increases in oxidative damage do not necessitate … to oxidative stress given that
the cell may have increased its … increased flux of reactive oxygen responsible for the damage. …
the cell may have increased its … increased flux of reactive oxygen responsible for the damage. …
MPP+ increases the vulnerability to oxidative stress rather than directly mediating oxidative damage in human neuroblastoma cells
HS Lee, CW Park, YS Kim - Experimental Neurology, 2000 - Elsevier
… no increase in lipid peroxidation, a sign of oxidative damage. Our results indicate that MPP at
neurotoxic concentrations did not provoke oxidative damage… to assess oxidative damage to …
neurotoxic concentrations did not provoke oxidative damage… to assess oxidative damage to …
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