HTLV-1 viral factor HBZ induces CCR4 to promote T-cell migration and proliferation

K Sugata, J Yasunaga, H Kinosada, Y Mitobe, R Furuta… - Cancer research, 2016 - AACR
… that HBZ RNA and protein both increase CCR4 expression through upregulated GATA3
expression. HBZ-induced CCR4 expression is implicated in the migration of T cells. Importantly, …

Molecular mechanisms of HTLV-1 cell-to-cell transmission

C Gross, AK Thoma-Kress - Viruses, 2016 - mdpi.com
… The authors proposed the model that p8 enhances transmission of HTLV-1 by increasing
We found that Fascin is also important for invasive migration of HTLV-1-infected cells [121]. …

[HTML][HTML] HTLV-1 infection: An emerging risk. Pathogenesis, epidemiology, diagnosis and associated diseases

E Eusebio-Ponce, E Anguita… - Revista Española de …, 2019 - ncbi.nlm.nih.gov
… infected individuals with infective dermatitis have an increase of HTLV-1 positive clones. …
Spain is not an endemic region for HTLV-1, but it receives a large influx migration from highly …

Current status of HTLV-1 infection

T Watanabe - International journal of hematology, 2011 - Springer
… The number has increased in the metropolitan areas, probably reflecting the migration of …
data in countries where HTLV-1 is endemic, and re-evaluation of HTLV-1 infection is required …

The neurology of HTLV-1 infection

SA Cooper, MS van der Loeff, GP Taylor - Practical neurology, 2009 - pn.bmj.com
HTLV-1 prevalence). Following increased migration in the last five centuries, HTLV-1 has
reached Europe but remains uncommon in the general population Nonetheless, HTLV-1 in …

Gem-induced cytoskeleton remodeling increases cellular migration of HTLV-1-infected cells, formation of infected-to-target T-cell conjugates and viral transmission

SA Chevalier, J Turpin, A Cachat, PV Afonso… - PLoS …, 2014 - journals.plos.org
… Thus, we hypothesize that the enhanced cell migration upon HTLV-1 infection increases
the probability of encountering and infecting new target cells through the creation of cell-to-cell …

JAG1 overexpression contributes to Notch1 signaling and the migration of HTLV-1-transformed ATL cells

M Bellon, R Moles, H Chaib-Mezrag… - Journal of Hematology & …, 2018 - Springer
… We next investigated the molecular mechanism associated with increased JAG1
expression in HTLV-I-transformed cell lines. The viral Tax gene encodes for a 40-kDa nuclear …

Factors predisposing to HTLV-1 infection in residents of the greater Tokyo area

K Uchimaru, Y Nakamura, A Tojo, T Watanabe… - International journal of …, 2008 - Springer
… to HTLV-1 infection including the birthplaces of HTLV-1 infected … to estimate the effect of
migration to greater Tokyo. Of 88 … of HTLV-1 carriers from endemic areas is increasing in greater …

HTLV-1 and HTLV-2 infection among Warao indigenous refugees in the Brazilian Amazon: challenges for public health in times of increasing migration

IN Abreu, FT Lopes, CNC Lima, AN Barbosa… - Frontiers in Public …, 2022 - frontiersin.org
… between the sequences described in the present study (HTLV-1 - BRPA_31564 and
HTLV-2 – BRPA_31238) and those available in GenBank for HTLV-1 (BRPA; 146, BRPA; 180, …

HTLV-1 bZIP factor dysregulates the Wnt pathways to support proliferation and migration of adult T-cell leukemia cells

G Ma, J Yasunaga, J Fan, S Yanagawa, M Matsuoka - Oncogene, 2013 - nature.com
… analyses revealed increased expression of Wnt5a in HTLV-1-… cell migration using a
trans-well T-cell migration assay (… antibody to Wnt5a on migration of HTLV-1-infected cell lines. …