Overview of incretin hormones

S Efendic, N Portwood - Hormone and Metabolic Research, 2004 - thieme-connect.com
… seem to be a physiological incretin hormone, since carefully … insulin secretion, and
CCK-receptor antagonism does not reduce … -1 are the hormones that mediate incretin-specific …

The alpha‐7 nicotinic acetylcholine receptor agonist GTS‐21 engages the glucagon‐like peptide‐1 incretin hormone axis to lower levels of blood glucose in db/db …

Q Meng, OG Chepurny, CA Leech… - Diabetes, Obesity …, 2022 - Wiley Online Library
… Because GTS-21 also raises levels of circulating GLP-1 while failing to increase insulin
sensitivity, we propose that GTS-21 engages the GLP-1 incretin hormone axis to stimulate …

From organophosphate poisoning to diabetes mellitus: The incretin effect

D Rathish, SB Agampodi, M Jayasumana… - Medical …, 2016 - Elsevier
receptors. We hypothesize that OP poisoning leads to disruption of glucose homeostasis by
attenuation of the incretin … will open possibility of using incretin based treatment modalities to …

What do we know about the secretion and degradation of incretin hormones?

CF Deacon - Regulatory peptides, 2005 - Elsevier
… activation of alpha adrenergic receptors [55]. Non-adrenergic non-cholinergic innervation
has also been proposed to be involved in regulation of incretin hormone secretion, and gastrin-…

Therapeutic potential of α7 nicotinic acetylcholine receptor agonists to combat obesity, diabetes, and inflammation

H Xie, N Yepuri, Q Meng, R Dhawan, CA Leech… - Reviews in Endocrine …, 2020 - Springer
… Vagovagal reflexes are an integral component of CAIR whose anti-inflammatory effects
are mediated by acetylcholine (ACh) acting at α7 nicotinic acetylcholine receptors (α7nAChR) …

Incretin hormones and the satiation signal

JJ Holst - International journal of obesity, 2013 - nature.com
… The incretin hormones are gut hormones that amplify nutrient-induced insulin secretion
in response to meal intake. Glucagon-like peptide-1 (GLP-1) and glucose-dependent …

Effects of obesity induced by high-calorie diet and its treatment with exenatide on muscarinic acetylcholine receptors in rat hippocampus

MFP Silva, PL Alves, RF Alponti, PF Silveira… - Biochemical …, 2019 - Elsevier
… The GLP-1 receptor is expressed in several regions of rodent and human brain, including …
between the cholinergic neurotransmitters acetylcholine and the incretin hormone GLP-1 on …

α7 Nicotinic Acetylcholine Receptor Regulates the Function and Viability of L Cells

D Wang, Q Meng, CA Leech, N Yepuri, L Zhang… - …, 2018 - academic.oup.com
incretin hormone glucagon-like peptide-1 (GLP-1), and they also express the α7 nicotinic
acetylcholine receptor … Glucagon-like peptide-1 (GLP-1) is an incretin hormone that is produced …

… enhancement of insulinotropic action of GLP-1 by acetylcholine uncovers paradoxical inhibitory effect of beta cell muscarinic receptor activation on adenylate cyclase …

JC Miguel, YHA Abdel-Wahab, BD Green… - Biochemical …, 2003 - Elsevier
… cooperation between the cholinergic neurotransmitter ACh and the incretin hormone GLP-1
on insulin secretion mediated through the M3 muscarinic receptor subtype. However, the …

Control of glucose homeostasis by incretin hormones

R Perfetti, TA Brown, R Velikina… - Diabetes Technology & …, 1999 - liebertpub.com
… were referred to as incretins. This research established the importance of the hormones of
the … Since the early identification of the “incretin effect,” more than 20 peptides physiologically …