Tachykinins and their receptors: contributions to physiological control and the mechanisms of disease

MS Steinhoff, B von Mentzer, P Geppetti… - Physiological …, 2014 - journals.physiology.org
tachykinins and NKRs to pathophysiological control. We summarize the discovery, structure,
and function of tachykinins and their receptorsmechanisms and importance of tachykinins in …

Neurokinin B induces oedema formation in mouse lung via tachykinin receptorindependent mechanisms

AD Grant, R Akhtar, NP Gerard… - The Journal of …, 2002 - Wiley Online Library
… in skin is mediated via NK 1 receptors, whilst plasma extravasation observed in … a tachykinin
receptor-independent mechanism, as observed using selective antagonists in NK 1 receptor

Tachykinin receptors as therapeutic targets in stress-related disorders

K Ebner, SB Sartori, N Singewald - Current pharmaceutical …, 2009 - ingentaconnect.com
… raphe and essential integrity of NA neurons (largely independent of 5-HT1A receptors) have
been identified as mechanisms contributing to the increased 5-HT activity by sustained NK1 …

Peripheral tachykinin receptors as targets for new drugs

R Patacchini, CA Maggi - European journal of pharmacology, 2001 - Elsevier
… an indomethacin-insensitive effector mechanism, whereas tachykinin NK 2 receptor-mediated
ion … intracellular effector mechanisms are triggered by the tachykinin NK 2 receptor in the …

Tachykinins and tachykinin receptors: structure and activity relationships

TA Almeida, J Rojo, PM Nieto, FM Pinto… - Current medicinal …, 2004 - ingentaconnect.com
… their specific membrane receptors. In … tachykinins and their receptors are of peptide origin,
we will summarize the current knowledge on evolution of tachykinin and tachykinin receptor

Substance P, neurokinins A and B, and synthetic tachykinin peptides protect mesencephalic dopaminergic neurons in culture via an activity-dependent mechanism

B Salthun-Lassalle, S Traver, EC Hirsch… - Molecular pharmacology, 2005 - ASPET
… DA neurons rescued by tachykinins accumulated [ 3 H]… tachykinins was highly selective for
DA neurons, rapidly reversed upon treatment withdrawal, and reproduced by but independent

Tachykinin receptors antagonism for asthma: a systematic review

R Ramalho, R Soares, N Couto, A Moreira - BMC pulmonary medicine, 2011 - Springer
… Recently, a model of interaction between different pathophysiologic mechanisms known to
affect … Two reviewers (RR and NC) applied the inclusion criteria independently and where …

Tachykinin receptors in the gut: physiological and pathological implications

P Holzer, U Holzer-Petsche - Current opinion in pharmacology, 2001 - Elsevier
… determines their affinity for tachykinin receptors (Fig. 1). Following the identification of three
tachykinin receptor genes, exceptional progress has been made in tachykinin pharmacology, …

Tachykinins and tachykinin receptors: a growing family

JN Pennefather, A Lecci, ML Candenas, E Patak… - Life sciences, 2004 - Elsevier
tachykinin receptors exist. In this review, we summarize the current knowledge of tachykinins
and their receptors… and liver by a mechanism independent of the three known tachykinin

Pharmacological mechanisms of 5-HT3 and tachykinin NK1 receptor antagonism to prevent chemotherapy-induced nausea and vomiting

C Rojas, BS Slusher - European journal of pharmacology, 2012 - Elsevier
receptor internalization could be occurring with any of these three receptor antagonists, a
series of four independent … cells expressing the 5-HT 3 receptor for as little as 15 min followed …