… this assay in the past 25 years. In addition, we present an example of how the comet assay
… of DNA damage in human lung cancer cells after differing doses of the cytosine analog 5-aza-…

… comet assay, a gel electrophoresis–based method that can be used to measure DNA damage
in individual eukaryotic cells… diploid mammalian cell. DNA damage and its repair in single-…

… comet assay is a single-cell gel electrophoresis initial levels of DNA damage in individual
cells … provided an opportunity to examine a number and repair of damage, in individual cells. It …

… was developed many years ago to analyze DNA damage in individual cells. It is a powerful
and versatile technique that relies on microscopic visualization or imaging of DNA after …

… culture, suspension cell culture, white blood cells, and tissue. Comet assays measure DNA
damage in individual cells; thus, single-cell suspensions need to be prepared. To minimize …

… inter-individual range of damage levels within any group—as well as intra-individual variability
… to assess individual risk of diseases such as cancer from comet assay results would be …

… comet assay is a gel electrophoresis method that is used to visualize and measure DNA strand
breaks in individual cells … breaks in individual cells using microscopy. In its simplest form, …

… relationships to compare with cellular endpoints. We have used the single-cell gel electrophoresis
(SCGE) or `comet' assay to measure DNA damage in individual cells after irradiation. …

… The purpose of this review is to clear up some misconceptions about the comet assay and to
… : detection of maturation of recently replicated DNA in individual cells. Cancer Res. 59, 5912…

… The assay has also been successfully implemented in plant cells under laboratory … of the
Comet Assay include: (a) the collection of data at the level of the individual cell, allowing more …