… (propofol syndrome) related to the use of propofol have been reported. In the present study,
the individual differences in pharmacokinetics and/or pharmacodynamics of propofol were …

… Propofol is a potent intravenous hypnotic drug. It exerts its … pharmacokinetic (PK) and
pharmacodynamic (PD) propofol … Defining the nature of interaction between propofol and other …

… , although large inter-individual differences in dose … propofol pharmacokinetics was
simultaneously examined. This study aimed to identify factors determining propofol pharmacokinetics…

… Individual differences in genetic factors [single nucleotide polymorphisms (SNPs)] in the
genes encoding metabolic enzymes, molecular transporters, and molecular binding sites …

… We aggregated and analyzed 21 previously published propofol datasets containing data
from young children, children, adults, elderly, and obese individuals. A 3-compartmental …

… in propofol metabolism. We have analysed the plasma pharmacokinetic profile of propofol
in 85 … As a parameter describing the pharmacokinetics in each patient, the MRT was finally …

… pharmacokinetic study on propofol disposition in preterm and term neonates confirmed the
overall lower propofol … Significant inter-individual variability (322%) in propofol clearance has …

… The aims of this study were to estimate the pharmacokinetics of propofol with special
respect to the covariates age, body weight, and gender and to evaluate the inter- and …

… The comparison of our model and the literature pharmacokinetic models of propofol (Schnider
[19], Bjornsson [5], Schuttler [21], Marsh [13] and Peeters [17]) for a 40-year-old male of 70 …

… The dataset alone did not enable us to correctly characterize the pharmacokinetics of
propofol. The parameter estimates resulted in comparable values with those in the literature only …