… With the complete sequence of the human genome available, individualized … individual's
drug response and selection of the appropriate drug dosage to achieve the optimal therapeutic …

… early attempts to individualize drug therapy. The modern era of individualized medicine can
be … of insulin became available for individualization of therapy, each with different absorption …

… Since 1965 there have been more than 800 pharmacogenetics/genomics reviews —
most suggesting that we are on the verge of offering individualized drug therapy to everyone. …

… drugs can hit a desired therapeutic goal. This book highlights the best methods that enable
individualized drug therapy … The book discusses where individualized therapy is currently …

… drug therapies will be realized, and will represent an important biomedical advance in the
post-genomics era. The results of drug therapy … can have minimal or no therapeutic response. …

… and monitoring of drugs commonly used in older patients. We also introduce the possible
role of … and therapeutic drug monitoring as tools to guide the individualization of drug therapy. …

… to individualize drug therapy in the present 'genomic' era. The application of genetic information
during the clinical therapeutic … appropriate care to each individual patient rather than a '…

… use of CYP genotypes to individualize treatments. It is now well … potential to individualize
treatments with certain drugs on the … genes encoding drug receptors in relation to individualized …

… We believe that transcriptomics is unlikely to play a major role in individualized drug therapy.
The reason involves the major limitation of microarray expression: the availability of the …

… drug side effects and for inefficient drug therapy. Hereditary variants in drug metabolizing
enzymes, drug transporters, and drug targets are important determinants of drug response and …