[HTML][HTML] Optimization of the enhanced permeability and retention effect for near-infrared imaging of solid tumors with indocyanine green

JX Jiang, JJ Keating, EM De Jesus… - American journal of …, 2015 - ncbi.nlm.nih.gov
… Our goal was to determine the optimal time and dose for imaging solid tumors using
Indocyanine Green. Syngeneic murine flank tumor models were used to test NIR imaging of ICG at …

Affinity of indocyanine green in the detection of colorectal peritoneal carcinomatosis: the role of enhanced permeability and retention effect

A Filippello, J Porcheron, JP Klein… - Surgical …, 2017 - journals.sagepub.com
Indocyanine green (ICG) is increasingly being used in … due to the enhanced permeability
and retention effect; however, this … the enhanced permeability and retention effect causes ICG …

Preferential tumor cellular uptake and retention of indocyanine green for in vivo tumor imaging

N Onda, M Kimura, T Yoshida… - International journal of …, 2016 - Wiley Online Library
Indocyanine green (ICG) is a fluorescent agent approved for clinical applications by the
Food and Drug Administration and … EPR effect enhanced permeability and retention effect

Indocyanine green retention rates at 15 min predicted hepatic decompensation in a western population

B Le Roy, E Grégoire, C Cossé, B Serji, N Golse… - World Journal of …, 2018 - Springer
… The aim of this study was to evaluate the relevance of indocyanine green retention rate at
15 min (ICGR15) before liver resection in Western countries, in order to predict HD. …

The value of intraoperative near-infrared fluorescence imaging based on enhanced permeability and retention of indocyanine green: feasibility and false-positives in …

QRJG Tummers, CES Hoogstins, AAW Peters… - PloS one, 2015 - journals.plos.org
… imaging and indocyanine green (ICG) as a result of enhanced permeability and retention
(… This phenomenon is called the "enhanced permeability and retention" (EPR) effect and has …

[HTML][HTML] Applications of indocyanine green based near-infrared fluorescence imaging in thoracic surgery

J Zhou, F Yang, G Jiang, J Wang - Journal of Thoracic Disease, 2016 - ncbi.nlm.nih.gov
… In this article, the current studies of indocyanine green (ICG) based NIR … and retention (EPR)
effect, and the other mechanisms. … on the enhanced permeability and retention (EPR) effect

Mechanisms of delayed indocyanine green fluorescence and applications to clinical disease processes

J Zajac, A Liu, S Hassan, A Gibson - Surgery, 2024 - Elsevier
… of indocyanine green retention at the cellular level to better understand the clinical nuances
of delayed indocyanine green … enhanced permeability and retention effect without providing …

Dynamic fluorescent imaging with indocyanine green for monitoring the therapeutic effects of photoimmunotherapy

T Ali, T Nakajima, K Sano, K Sato… - Contrast media & …, 2014 - Wiley Online Library
… dose of 50 J cm −2 is optimal for the permeability and retention effect, leading to a higher
leakage and uptake of ICG into the tumor bed. †, Marginally significant; * p < 0.05; ** p < 0.01. …

Indocyanine green: An old drug with novel applications

CH Lu, JK Hsiao - Tzu chi medical journal, 2021 - journals.lww.com
… ) Indocyanine green in the original constitution with the addition of sodium iodide, displaying
a dark brown color. (b) Indocyanine green … permeability and retention effect is believed to be …

Hybrid polypeptide micelles loading indocyanine green for tumor imaging and photothermal effect study

L Wu, S Fang, S Shi, J Deng, B Liu, L Cai - Biomacromolecules, 2013 - ACS Publications
… One of the properties of solid tumors is their enhanced permeation and retention (EPR)
effect, which allows a several hundred nanometer compound to extravagate from blood …