Monoterpenoid indole alkaloid adducts and dimers from Melodinus fusiformis

ZW Liu, M Song, JY Wang, DZ Wang, B Sun, L Shi… - Phytochemistry, 2023 - Elsevier
… of Melodinus fusiformis Champ. ex Benth. Compounds 1 and 2 are unusual hybrid indole
alkaloids incorporating an aspidospermatan-type MIA with a monoterpenoid alkaloid unit via C…

Chemical constituents of Melodinus hemsleyanus diels

JT Wang, LW Liang, FR Li, A Khan, L Liu… - … systematics and ecology, 2019 - Elsevier
… 21 have not previously been recorded in the genus Melodinus. The aspidosperma-type
monoterpenoid indole alkaloids in M. hemsleyanus could serve as chemotaxonomic markers. …

Potent immunosuppressive and anti-inflammatory bisindole alkaloids from Melodinus fusiformis

L Liu, MJ Xie, WB Zhou, JT Wang, JY Wang… - Natural Product …, 2022 - Taylor & Francis
… of 1 as an indole alkaloid dimer. Comparison and deduplication analysis of the 13 C NMR
spectra sugguested that the mono aspidosperma alkaloid was 19β-hydroxyvenalstonidine (…

Melotenuines AE, cytotoxic monoterpenoid indole alkaloids from Melodinus tenuicaudatus

JW Liu, ZQ Huo, Q Zhao, XJ Hao, HP He, Y Zhang - Fitoterapia, 2019 - Elsevier
indole alkaloids were isolated from the twigs and leaves of Melodinus tenuicaudatus. Reported
… are the isolation, structure elucidation, and cytotoxicity evaluation of the new alkaloids. …

Targeted isolation of terpenoid indole alkaloids from Melodinus cochinchinensis (Lour.) Merr. using molecular networking and their biological activities

F Li, Y Wang, S He, A Khan, Q Xue, Q Cui, L Liu… - Industrial Crops and …, 2020 - Elsevier
… This study was aimed to isolate terpenoid indole alkaloids (TIAs) from the aerial parts of M. …
our previously reported TIAs from the species of Melodinus. The structures of new TIAs were …

Phytochemical and pharmacological properties of the Genus Melodinus–a review

JH Jiang, WD Zhang, YG Chen - Tropical Journal of Pharmaceutical …, 2015 - ajol.info
… In this paper, indole alkaloids could be classified into ten groups from some Melodinus plants.
yunnanensis and concurring with previous in vivo tracer experiments in the literature [53]. …

Melognine, a novel monoterpenoid indole alkaloid from Melodinus fusiformis that induce apoptosis in BT549 cells

J Zhou, SY Du, ZY Fang, JH Feng - Natural Product Research, 2021 - Taylor & Francis
… monoterpenoid indole alkaloid, melognine (1) possessing an unprecedented skeleton with
a 6/6/5/5/6/6 hexatomic rearranged ring system was isolated from the stems of Melodinus

Chemical constituents and anti-inflammatory activity of the total alkaloid extract from Melodinus cochinchinensis (Lour.) Merr. and its inhibition of the NF-κB and MAPK …

M Yang, Y Wang, Z Fan, Q Xue, GSS Njateng, Y Liu… - Phytomedicine, 2021 - Elsevier
… A total of 21 monoterpenoid indole alkaloids (MIAs) were characterized by UHPLC-ESI-…
A total of 21 indole alkaloids were unambiguously identified as 10-hydroxyscandine (1), …

HRESIMS-guided isolation of aspidosperma-scandine type bisindole alkaloids from Melodinus cochinchinensis and their anti-inflammatory and cytotoxic activities

FR Li, L Liu, YP Liu, JT Wang, ML Yang, A Khan… - Phytochemistry, 2021 - Elsevier
… As an extension of our ongoing search for structurally unique and bioactive indole alkaloids,
the BIAs in the alkaloidal extracts from the leaves and stems of M. cochinchinensis were …

Chemical constituents from Melodinus cochinchinensis (Lour.) Merr. and their chemotaxonomic significance

L Yang, JJ He, XY Cui, YP Liu, B Wang - Biochemical Systematics and …, 2021 - Elsevier
yunnanensis are similar and the species are rich in monoterpenoid indole alkaloids. …
The aspidospermine type indole alkaloid is the largest group of alkaloids in the genus …