Marine indole alkaloids: potential new drug leads for the control of depression and anxiety

AJ Kochanowska-Karamyan, MT Hamann - Chemical reviews, 2010 - ACS Publications
… In this review, we have discussed 46 natural indole alkaloids of marine origin and 87
synthetic molecules. The synthesis of monoindole alkaloids was in many cases inspired by the …

[HTML][HTML] Indole alkaloids from plants as potential leads for antidepressant drugs: A mini review

HA Hamid, ANM Ramli, MM Yusoff - Frontiers in pharmacology, 2017 - frontiersin.org
indole alkaloids isolated with antidepressant activity. This review provides information on the
potential of natural indole alkaloids … metabolites as potential antidepressant drug leads from …

[HTML][HTML] Indole alkaloids from marine sources as potential leads against infectious diseases

PHB França, DP Barbosa, DL da Silva… - BioMed research …, 2014 - hindawi.com
… Therefore this review highlighted some marine indole alkaloids which may be considered
as potential starting points for the development of novel agents for the treatment of infectious …

Therapeutic potential of indole alkaloids in respiratory diseases: A comprehensive review

S Mitra, SR Prova, SA Sultana, R Das, F Nainu… - Phytomedicine, 2021 - Elsevier
… the in-depth therapeutic potential of indole alkaloids against various respiratory disorders. …
This review also discusses clinical studies exploring the therapeutic efficacy of indole alkaloids

Indole alkaloid marine natural products: An established source of cancer drug leads with considerable promise for the control of parasitic, neurological and other …

W Gul, MT Hamann - Life sciences, 2005 - Elsevier
… of new drug leads. This report reviews the literature on indole alkaloids of marine origin and
also highlights our own research. Specific biological activities of indole alkaloids presented …

Potential antimalarial activity of indole alkaloids

M Frederich, M Tits, L Angenot - … of the royal society of tropical …, 2008 - academic.oup.com
… plants and marine organisms could provide new leads to antimalarial drugs. The natural …
, we will focus on indole alkaloids that show antiplasmodial properties. The alkaloids are a …

Indole alkaloids: 2012 until now, highlighting the new chemical structures and biological activities

PF Rosales, GS Bordin, AE Gower, S Moura - Fitoterapia, 2020 - Elsevier
… The indole alkaloids, which have tryptophan or tryptamine as … a large structural variety of
indole alkaloids, which support … and biological activities of new indoles alkaloids. Databases, …

[HTML][HTML] The therapeutic prospects of naturally occurring and synthetic indole alkaloids for depression and anxiety disorders

S Munir, A Shahid, B Aslam, UA Ashfaq… - Evidence-Based …, 2020 - hindawi.com
… Structure and Function of Indole Alkaloids Indole alkaloids (IAs) are bicyclic compounds …
e presence of nitrogen atom in the pyrrole ring leads to the basic characteristics of IAs making …

The indole 2-3-quinodimethane strategy for the synthesis of indole alkaloids

P Magnus, T Gallagher, P Brown… - Accounts of Chemical …, 1984 - ACS Publications
The chemistry of alkaloids has been historically central to the development of classical
methods of structural elucidation and synthesis in organicchem-istry. Many well-known and …

Indole alkaloids and semisynthetic indole derivatives as multifunctional scaffolds aiming the inhibition of enzymes related to neurodegenerative diseases–a focus on …

L Carlos Klein-Junior… - Current Topics in …, 2014 - ingentaconnect.com
Indole alkaloids and synthetic indole derivatives are well known for their therapeutic … Here,
we overview the multifunctional potential of these molecules for the inhibition of enzymes …