[HTML][HTML] Naturally derived indole alkaloids targeting regulated cell death (RCD) for cancer therapy: from molecular mechanisms to potential therapeutic targets
R Qin, FM You, Q Zhao, X Xie, C Peng, G Zhan… - Journal of hematology & …, 2022 - Springer
… olaparib) to exhibit therapeutic potential against various cancers … death by indole alkaloids
against different targets is expected to … the development of new strategies for cancer therapy. …
against different targets is expected to … the development of new strategies for cancer therapy. …
[HTML][HTML] Indole-based small molecules as potential therapeutic agents for the treatment of fibrosis
R Qin, Q Zhao, B Han, HP Zhu, C Peng… - Frontiers in …, 2022 - frontiersin.org
… the potential of natural indole alkaloids, semi-synthetic indole alkaloids, synthetic indole
derivatives, and indole-… is to verify the therapeutic effects and activities of indole alkaloids and its …
derivatives, and indole-… is to verify the therapeutic effects and activities of indole alkaloids and its …
Therapeutic potential of indole alkaloids in respiratory diseases: A comprehensive review
… This review also discusses clinical studies exploring the therapeutic efficacy of indole
alkaloids, which have confirmed the promising benefits observed in vivo and in vitro. …
alkaloids, which have confirmed the promising benefits observed in vivo and in vitro. …
[HTML][HTML] Advances in indole-containing alkaloids as potential anticancer agents by regulating autophagy
ML Luo, W Huang, HP Zhu, C Peng, Q Zhao… - Biomedicine & …, 2022 - Elsevier
… indole alkaloids' effect on tumor cells and autophagy. Then, we focus on mechanisms by
which indole alkaloids can target … The study about IADB may support novel therapeutic targets …
which indole alkaloids can target … The study about IADB may support novel therapeutic targets …
[HTML][HTML] The therapeutic prospects of naturally occurring and synthetic indole alkaloids for depression and anxiety disorders
… However, studies on the antidepressant potential of indole alkaloids from plants or … the
potential of indole alkaloids from plants and of marine origin as well as synthetic indole alkaloids …
potential of indole alkaloids from plants and of marine origin as well as synthetic indole alkaloids …
[HTML][HTML] Research progress of indole alkaloids: targeting MAP kinase signaling pathways in cancer treatment
… indole alkaloids affect the MAPK signaling pathway in cancer treatment and focus on
advancements in the role of indole alkaloids… indole alkaloids to achieve the desired therapeutic …
advancements in the role of indole alkaloids… indole alkaloids to achieve the desired therapeutic …
Alkaloids for cancer prevention and therapy: Current progress and future perspectives
A Mondal, A Gandhi, C Fimognari, AG Atanasov… - European journal of …, 2019 - Elsevier
… Fascaplysin, an indole alkaloid isolated from marine sponge, … Fourteen indole alkaloids
were extracted from the stem and … Indole alkaloids coronaridine, voacangine and heyneanine …
were extracted from the stem and … Indole alkaloids coronaridine, voacangine and heyneanine …
[HTML][HTML] Update of Indoles: Promising molecules for ameliorating metabolic diseases
W Hu, G Yan, Q Ding, J Cai, Z Zhang, Z Zhao… - Biomedicine & …, 2022 - Elsevier
… Among all kinds of alkaloids, indole alkaloids, related to the … Indole alkaloids are generally
extracted from the plant … As pharmacologically active secondary metabolites, indole alkaloids …
extracted from the plant … As pharmacologically active secondary metabolites, indole alkaloids …
[HTML][HTML] Ajmalicine and reserpine: Indole alkaloids as multi-target directed ligands towards factors implicated in Alzheimer's disease
P Kashyap, V Kalaiselvan, R Kumar, S Kumar - Molecules, 2020 - mdpi.com
… in the current study, are indole alkaloids; reserpine (RES) and … -target drug ligand potential
of reserpine and ajmalicine. The selected compounds demonstrated to bind with AD targets …
of reserpine and ajmalicine. The selected compounds demonstrated to bind with AD targets …
Marine indole alkaloids: potential new drug leads for the control of depression and anxiety
AJ Kochanowska-Karamyan, MT Hamann - Chemical reviews, 2010 - ACS Publications
… In this review, we have discussed 46 natural indole alkaloids of marine origin and 87
synthetic molecules. The synthesis of monoindole alkaloids was in many cases inspired by the …
synthetic molecules. The synthesis of monoindole alkaloids was in many cases inspired by the …
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